Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김교상 | - |
dc.date.accessioned | 2018-03-14T02:37:35Z | - |
dc.date.available | 2018-03-14T02:37:35Z | - |
dc.date.issued | 2014-06 | - |
dc.identifier.citation | Korean Journal of Anesthesiology, 권: 66, 호: 6, 페이지: 451-456 | en_US |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ekja.org/journal/view.php?doi=10.4097/kjae.2014.66.6.451 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/46491 | - |
dc.description.abstract | Background: Succinylcholine commonly produces frequent adverse effects, including muscle fasciculation and myalgia. The current study identified the optimal dose of rocuronium to prevent succinylcholine-induced fasciculation and myalgia and evaluated the influence of rocuronium on the speed of onset produced by succinylcholine.Methods: This randomized, double-blinded study was conducted in 100 patients randomly allocated into five groups of 20 patients each. Patients were randomized to receive 0.02, 0.03, 0.04, 0.05 and 0.06 mg/kg rocuronium as a precurarizing dose. Neuromuscular monitoring after each precurarizing dose was recorded from the adductor pollicis muscle using acceleromyography with train-of-four stimulation of the ulnar nerve. All patients received succinylcholine 1.5 mg/kg at 2 minutes after the precurarization, and were assessed the incidence and severity of fasciculations, while myalgia was assessed at 24 hours after surgery.Results: The incidence and severity of visible muscle fasciculation was significantly less with increasing the amount of precurarizing dose of rocuronium (P < 0.001). Those of myalgia tend to decrease according to increasing the amount of precurarizing dose of rocuronium, but there was no significance (P = 0.072). The onset time of succinylcholine was significantly longer with increasing the amount of precurarizing dose of rocuronium (P < 0.001).Conclusions: Precurarization with 0.04 mg/kg rocuronium was the optimal dose considering the reduction in the incidence and severity of fasciculation and myalgia with acceptable onset time, and the safe and effective precurarization. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Korean Society Of Anesthesiologists | en_US |
dc.subject | Fasciculation | en_US |
dc.subject | Myalgia | en_US |
dc.subject | Neuromuscular blockade | en_US |
dc.subject | Precurarization | en_US |
dc.subject | Rocuronium | en_US |
dc.subject | Succinylcholine. | en_US |
dc.title | Optimal precurarizing dose of rocuronium to decrease fasciculation and myalgia following succinylcholine administration | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 66 | - |
dc.identifier.doi | 10.4097/kjae.2014.66.6.451 | - |
dc.relation.page | 451-456 | - |
dc.relation.journal | Korean Journal of Anesthesiology | - |
dc.contributor.googleauthor | 김규남 | - |
dc.contributor.googleauthor | 최훈일 | - |
dc.contributor.googleauthor | 정지선 | - |
dc.contributor.googleauthor | 이희종 | - |
dc.contributor.googleauthor | Kim, Kyo-Sang | - |
dc.relation.code | 2014015879 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kimks | - |
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