Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 배현주 | - |
dc.date.accessioned | 2018-03-13T02:13:35Z | - |
dc.date.available | 2018-03-13T02:13:35Z | - |
dc.date.issued | 2013-06 | - |
dc.identifier.citation | Infection, June 2013, 41(3), p.603-612 | en_US |
dc.identifier.issn | 1439-0973 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007%2Fs15010-013-0441-z | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/45757 | - |
dc.description.abstract | The aim of this study was to determine the risk factors and clinical characteristics of community-acquired acute pyelonephritis (CA-APN) caused by extended-spectrum β-lactamase (ESBL)-producing organisms.MethodsFrom March 2010 to February 2011, patients with CA-APN were recruited in 11 hospitals in South Korea. Clinical and microbiological data were collected prospectively, and the ESBLs and multilocus sequence types of the ESBL-producing Escherichia coli were characterized. Comparison between CA-APN caused by ESBL-producing Enterobacteriaceae and those by non-ESBL-producing organisms was performed.ResultsA total of 566 patients were recruited. Enterobacteriaceae were detected in 526 patients. Forty-six isolates (46/526, 8.7 %) were positive for ESBLs. Clinical and microbiological failure did not differ between the two groups, despite there being fewer patients with ESBL-positive isolates provided with appropriate antibiotics initially (19.6 vs. 93.8 %, p < 0.001). However, the duration of hospitalization was longer in the ESBL group (10.5 vs. 7.0 days, p = 0.012). In a logistic regression model, Charlson score ≥1 point [odds ratio (OR) 3.4, 95 % confidence interval (CI) 1.6?7.0, p = 0.001], antibiotics usage during the previous year (OR 3.1, 95 % CI 1.4?7.2, p = 0.008), and urinary catheterization during the previous month (OR 4.4, 95 % CI 1.1?17.6, p = 0.035) were associated with the risks of CA-APN by ESBL producers. CTX-M-15 (48 %) and CTX-M-14 (38 %) were the most common ESBLs. ST131 was the most common clone (7/24, 29.1 %), which was more frequently resistant to cefepime, fosfomycin, and temocillin.ConclusionsThe risk factors for CA-APN by ESBL producers were Charlson score ≥1 point, antibiotics usage during the previous year, and urinary catheterization during the previous month. | en_US |
dc.description.sponsorship | This work was supported by a grant from the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Science + Business Media | en_US |
dc.subject | Extended-spectrum β-lactamase | en_US |
dc.subject | Urinary tract infection | en_US |
dc.subject | Community acquired | en_US |
dc.subject | Risk factor | en_US |
dc.title | Clinical characteristics of community-acquired acute pyelonephritis caused by ESBL-producing pathogens in South Korea | en_US |
dc.type | Article | en_US |
dc.relation.volume | 41 | - |
dc.identifier.doi | 10.1007/s15010-013-0441-z | - |
dc.relation.page | 603-612 | - |
dc.relation.journal | INFECTION | - |
dc.contributor.googleauthor | Kim, B. | - |
dc.contributor.googleauthor | Kim, J | - |
dc.contributor.googleauthor | Seo, M.-R | - |
dc.contributor.googleauthor | Pai, H. | - |
dc.contributor.googleauthor | Wie, S.-H. | - |
dc.contributor.googleauthor | Cho, Y.K. | - |
dc.contributor.googleauthor | Lim, S.-K. | - |
dc.contributor.googleauthor | Lee, J.S. | - |
dc.contributor.googleauthor | Kwon, K.T. | - |
dc.contributor.googleauthor | Lee, H. | - |
dc.relation.code | 2013010252 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | paihj | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.