Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems
- Title
- Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems
- Author
- 하태경
- Keywords
- Accuracy; C-arm cone-beam CT; Lung biopsy; Small lung nodule; Virtual navigation guidance
- Issue Date
- 2013-08
- Publisher
- Springer Science + Business Media
- Citation
- European Radiology, Aug 2013, 23(3), P.712-719. 8P.
- Abstract
- Objectives: To describe our initial experience with percutaneous transthoracic needle biopsy (PCNB) of small (≤1 cm) lung nodules using a cone-beam computed tomography (CBCT) virtual navigation guidance system in 105 consecutive patients. Methods: One hundred and five consecutive patients (55 male, 50 female; mean age, 62 years) with 107 small (≤1 cm) lung nodules (mean size, 0.85 cm ± 0.14) underwent PCNBs under CBCT virtual-navigation guidance system and constituted our study population. Procedural details-including radiation dose, sensitivity, specificity, diagnostic accuracy and complication rates of CBCT virtual navigation guided PCNBs-were described. Results: The mean number of pleural passages with the coaxial needle, biopsies, CT acquisitions, total procedure time, coaxial introducer dwelling time, and estimated radiation exposure during PCNBs were 1.03 ± 0.21, 3.1 ± 0.7, 3.4 ± 1.3, 10.5 min ± 3.2 and 7.2 min ± 2.5, and 5.72 mSv ± 4.19, respectively. Sixty nodules (56.1 %) were diagnosed as malignant, 38 (35.5 %) as benign and nine (8.4 %) as indeterminate. The sensitivity, specificity, and diagnostic accuracy of CBCT virtual-navigation-guided PCNB for small (≤1 cm) nodules were 96.7 % (58/60), 100 % (38/38) and 98.0 % (96/98), respectively. Complications occurred in 13 (12.1 %) cases; pneumothorax in seven (6.5 %) and haemoptysis in six (5.6 %). Conclusion: CBCT virtual-navigation-guided PCNB is a highly accurate and safe diagnostic method for small (≤1 cm) nodules. Key Points: ? CBCT virtual-navigation guidance offers new biopsy options for lung nodules ? CBCT virtual-navigation-guided PCNB is highly accurate for small (≤1 cm) nodules ? CBCT virtual-navigation-guided PCNB for small (≤1 cm) nodules is safe ? Procedure time and radiation exposure of CBCT virtual-navigation-guided PCNB is reasonable [ABSTRACT FROM AUTHOR]
- URI
- https://link.springer.com/article/10.1007%2Fs00330-012-2644-6http://hdl.handle.net/20.500.11754/45047
- ISSN
- 0938-7994
- DOI
- 10.1007/s00330-012-2644-6
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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