Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김용태 | - |
dc.date.accessioned | 2018-03-09T05:41:02Z | - |
dc.date.available | 2018-03-09T05:41:02Z | - |
dc.date.issued | 2013-04 | - |
dc.identifier.citation | UROLOGIA INTERNATIONALIS, April 2013, 90(3), P.301-305 | en_US |
dc.identifier.issn | 0042-1138 | - |
dc.identifier.uri | https://www.karger.com/Article/Abstract/345292 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/44208 | - |
dc.description.abstract | Introduction: The aim of this study was to identify patients with low-volume Gleason score 3+4 (GS3+4) prostate cancer (PCa) who may be candidates for active surveillance (AS) by analyzing the incidence of upgrading and upstaging following radical prostatectomy (RP). Patients and Methods: Of 907 patients who underwent RP at our institute over the last 5 years, 66 men diagnosed with low-volume GS3+4 PCa at needle biopsy were identified. The incidence of upstaging and upgrading was assessed. Results: The overall rate of upgrading and upstaging was 31.8 and 25.6%, respectively. Preoperative PSA levels were significantly higher in patients who were upgraded (p = 0.015). The optimal preoperative PSA cutoff level for the prediction of upgrading was 4.73 ng/ml (sensitivity 85.7%, specificity 57.8%). Patients with <15% of maximum cores positive had significantly lower upstaging rate than those with >15% of maximum cores positive (p = 0.035). Clinical stage and number of positive cores had marginal association with upgrading and upstaging statistically (p = 0.061 and 0.081, respectively). Conclusions: In patients with low-volume GS3+4 PCa at biopsy, underestimation may be effectively avoided when we select patients with PSA <4.73 and % maximum cancer involvement on positive cores <15%. Copyright (C) 2013 S. Karger AG, Basel | en_US |
dc.description.sponsorship | Tanzman Foundation Jon Runyan's Score for the Cure National Research Foundation of Korea (NRF) Ministry of Education, Science and Technology Next-Generation BioGreen 21 Program, Rural Development Administration, Republic of Korea | en_US |
dc.language.iso | en | en_US |
dc.publisher | Karger | en_US |
dc.subject | Prostate cancer | en_US |
dc.subject | Active surveillance | en_US |
dc.subject | Gleason score 3+4 | en_US |
dc.subject | Radical prostatectomy | en_US |
dc.title | Incidence of Upgrading and Upstaging in Patients with Low-Volume Gleason Score 3+4 Prostate Cancers at Biopsy: Finding a New Group Eligible for Active Surveillance | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 90 | - |
dc.identifier.doi | 10.1159/000345292 | - |
dc.relation.page | 301-305 | - |
dc.relation.journal | UROLOGIA INTERNATIONALIS | - |
dc.contributor.googleauthor | Park, Hee Jung | - |
dc.contributor.googleauthor | Ha, Yun-Sok | - |
dc.contributor.googleauthor | Park, Sung Yul | - |
dc.contributor.googleauthor | Kim, Yong Tae | - |
dc.contributor.googleauthor | Lee, Tchun Yong | - |
dc.contributor.googleauthor | Kim, Jeong Hyun | - |
dc.contributor.googleauthor | Lee, Dong-Hyeon | - |
dc.contributor.googleauthor | Kim, Wun-Jae | - |
dc.contributor.googleauthor | Kim, Isaac Yi | - |
dc.relation.code | 2013008392 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | ytkimuro | - |
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