A Randomized, Multi-center, Phase IV Open-label Study to Evaluate and Compare the Effect of Carvedilol versus Propranolol on Reduction in Portal Pressure in Patients with Cirrhosis: an Interim Analysis

Abstract

Background: Recently, long-term low dose of carvedilol has suggested an option for primary prophylaxis of bleeding in patients with high-risk esophageal varices. The aim of this study is to evaluate and compare the effect of carvediolol versus pro-pranolol on reduction in portal pressure in patients with cirrhosis.