Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 정언석 | - |
dc.date.accessioned | 2018-03-06T01:52:20Z | - |
dc.date.available | 2018-03-06T01:52:20Z | - |
dc.date.issued | 2016-03 | - |
dc.identifier.citation | MEDICINE, v.95, no.9, p e2992 | en_US |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | http://ovidsp.tx.ovid.com/sp-3.28.0a/ovidweb.cgi?QS2=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 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/42825 | - |
dc.description.abstract | This is an observational study to determine the most relevant parameter of F-18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for predicting recurrence in cervical cancer. Fifty-six patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIB-IVA cervical cancer who underwent pretreatment (18) F-FDG PET/CT were enrolled. PET parameters including maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) of both primary tumor and pelvic and/or para-aortic lymph nodes were analyzed. SUVmax-S was defined as the sum of the SUVmax of primary tumor and the higher SUVmax of either pelvic or para-aortic lymph nodes. MTV-S was defined as the sum of the MTV of primary tumor and pelvic and para-aortic lymph nodes. TLG-S was calculated in the same way as MTV-S. We evaluated the relationship between these PET parameters and recurrence-free survival (RFS). Univariate analysis revealed that higher FIGO stage (hazard ratio [HR] = 5.61, 95% confidence interval [CI]: 1.68-18.68, P = 0.005), lymph node metastasis (HR = 3.42, 95% CI: 1.08-10.84, P = 0.037), MTV of primary tumor >47.81 cm(3) (HR = 6.20, 95% CI: 1.35-28.48, P = 0.019), TLG of primary tumor >215.02 (HR = 11.82, 95% CI: 1.52-91.96, P = 0.018), MTV-S >59.01 cm(3) (HR = 8.24, 95% CI: 1.80-37.77, P = 0.007), and TLG-S >224.15 (HR = 13.09, 95% CI: 1.68-101.89, P = 0.014) were associated with RFS. In multivariate analysis, FIGO stage (HR = 4.87, 95% CI: 1.38-17.18, P = 0.014) and MTV-S >59.01 cm(3) (HR = 7.37, 95% CI: 1.54-35.16, P = 0.012) were determined to be independent predictive factors for RFS. Our preliminary results reveal that MTV-S is an independent prognostic factor for RFS in patients with cervical cancer treated by definitive chemoradiotherapy. | en_US |
dc.description.sponsorship | This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number NRF-2013R1A1A2060431). | en_US |
dc.language.iso | en | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.subject | POSITRON-EMISSION-TOMOGRAPHY | en_US |
dc.subject | STANDARDIZED UPTAKE VALUE | en_US |
dc.subject | CARCINOMA | en_US |
dc.subject | METASTASES | en_US |
dc.subject | FLUORODEOXYGLUCOSE | en_US |
dc.subject | CHEMORADIOTHERAPY | en_US |
dc.subject | RECURRENCE | en_US |
dc.subject | THERAPY | en_US |
dc.subject | DISEASE | en_US |
dc.title | Prognostic Value of the Sum of Metabolic Tumor Volume of Primary Tumor and Lymph Nodes Using 18F-FDG PET/CT in Patients With Cervical Cancer | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1097/MD.0000000000002992 | - |
dc.relation.journal | MEDICINE | - |
dc.contributor.googleauthor | Hong, Jin Hwa | - |
dc.contributor.googleauthor | Min, Kyung Jin | - |
dc.contributor.googleauthor | Lee, Jae Kwan | - |
dc.contributor.googleauthor | So, Kyeong A | - |
dc.contributor.googleauthor | Jung, Un Suk | - |
dc.contributor.googleauthor | Kim, Sungeun | - |
dc.contributor.googleauthor | Eo, Jae Seon | - |
dc.relation.code | 2016002338 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
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