100 0

Full metadata record

DC FieldValueLanguage
dc.contributor.author윤태현-
dc.date.accessioned2018-02-28T06:39:57Z-
dc.date.available2018-02-28T06:39:57Z-
dc.date.issued2012-08-
dc.identifier.citationCytometry Part A, Vol. 81 A, No. 8, August 2012, Pages 691-697en_US
dc.identifier.issn1552-4922-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/cyto.a.22079/full-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/41265-
dc.description.abstractA modified MTT protocol-based microfluidic image cytometry (mu FIC) was performed to assess Cd2+ induced cytotoxicity. The expanded capabilities of mu FIC, such as in situ measurement, high-throughput, and multiparametric analysis of adherent cells under precisely controlled chemical environments of microfluidic channels, were demonstrated in this study. Multiparametric analysis of mu FIC data has enabled us to categorize the progress of cell death into at least four different subgroups based on their morphology and metabolic activity. These advantages of the MTT-based mu FIC as a simpler, cheaper, and faster in vitro cell-based assay tool have many implications in biomedical, pharmaceutical, toxicological, and biological application areas, and we propose this technique as a future high throughputhigh content screening (HT-HCS) platform for cytotoxicity assays and drug screening. (c) 2012 International Society for Advancement of Cytometryen_US
dc.description.sponsorshipGrant sponsor: Korea Ministry of Envir-onment and The Eco-Technopia 21 Pro-ject; Grant number: 091-091-081en_US
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USAen_US
dc.subjectimage cytometryen_US
dc.subjectlab-on-a-chipen_US
dc.subjectMTT assayen_US
dc.subjectmicrofluidicsen_US
dc.subjectcytotoxicityen_US
dc.subjectHIGH-THROUGHPUTen_US
dc.subjectFLOW-CYTOMETRYen_US
dc.subjectASSAYSen_US
dc.subjectDEVICEen_US
dc.subjectCELLSen_US
dc.titleMultiparametric assessment of Cd2+ cytotoxicity using MTT-based microfluidic image cytometryen_US
dc.typeArticleen_US
dc.relation.no8-
dc.relation.volume81A-
dc.identifier.doi10.1002/cyto.a.22079-
dc.relation.page691-697-
dc.relation.journalCYTOMETRY PART A-
dc.contributor.googleauthorLim, Kook-Hee-
dc.contributor.googleauthorPark, Jonghoon-
dc.contributor.googleauthorRhee, Seog-Woo-
dc.contributor.googleauthorYoon, Tae-Hyun-
dc.relation.code2012211569-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF NATURAL SCIENCES[S]-
dc.sector.departmentDEPARTMENT OF CHEMISTRY-
dc.identifier.pidtaeyoon-
Appears in Collections:
COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > CHEMISTRY(화학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE