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dc.contributor.author이근용-
dc.date.accessioned2018-02-28T04:18:56Z-
dc.date.available2018-02-28T04:18:56Z-
dc.date.issued2011-05-
dc.identifier.citationMACROMOLECULAR BIOSCIENCE, 11, 5, 673-679en_US
dc.identifier.issn1616-5187-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/mabi.201000479/abstract-
dc.description.abstractThe effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin alpha 1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels significantly enhanced the adipogenic differentiation of human ASCs to exhibit higher expression levels of oil red O staining and adipogenic genes compared to those of the control group (unmodified gels). These results suggest potential applications of RGD-modified alginate gels for adipose tissue regeneration.en_US
dc.description.sponsorshipThis work was supported by a NationalResearch Foundation of Korea grant funded by the KoreanGovernment (NRF-2009-351-1-D00045) and supported by theParts and Materials Technology Development Program fundedby the Ministry of Knowledge Economy (MKE, Korea, No.10030914).en_US
dc.language.isoenen_US
dc.publisherWILEY-V C H VERLAG GMBH, BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYen_US
dc.subjectadhesionen_US
dc.subjectbiological applications of polymersen_US
dc.subjectbiomaterials; hydrogelsen_US
dc.subjecttissue engineeringen_US
dc.titleThe Effect of Conjugating RGD into 3D Alginate Hydrogels on Adipogenic Differentiation of Human Adipose-Derived Stromal Cellsen_US
dc.typeArticleen_US
dc.relation.no5-
dc.relation.volume11-
dc.identifier.doi10.1002/mabi.201000479-
dc.relation.page673-679-
dc.relation.journalMACROMOLECULAR BIOSCIENCE-
dc.contributor.googleauthorKang, Sun-Woong-
dc.contributor.googleauthorCha, Byung-Hyun-
dc.contributor.googleauthorPark, Honghyun-
dc.contributor.googleauthorPark, Kwang-Sook-
dc.contributor.googleauthorLee, Kuen Yong-
dc.contributor.googleauthorLee, Soo-Hong-
dc.relation.code2011212230-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF ENGINEERING[S]-
dc.sector.departmentDEPARTMENT OF BIOENGINEERING-
dc.identifier.pidleeky-
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COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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