Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이근용 | - |
dc.date.accessioned | 2018-02-28T04:18:56Z | - |
dc.date.available | 2018-02-28T04:18:56Z | - |
dc.date.issued | 2011-05 | - |
dc.identifier.citation | MACROMOLECULAR BIOSCIENCE, 11, 5, 673-679 | en_US |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | http://onlinelibrary.wiley.com/doi/10.1002/mabi.201000479/abstract | - |
dc.description.abstract | The effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin alpha 1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels significantly enhanced the adipogenic differentiation of human ASCs to exhibit higher expression levels of oil red O staining and adipogenic genes compared to those of the control group (unmodified gels). These results suggest potential applications of RGD-modified alginate gels for adipose tissue regeneration. | en_US |
dc.description.sponsorship | This work was supported by a NationalResearch Foundation of Korea grant funded by the KoreanGovernment (NRF-2009-351-1-D00045) and supported by theParts and Materials Technology Development Program fundedby the Ministry of Knowledge Economy (MKE, Korea, No.10030914). | en_US |
dc.language.iso | en | en_US |
dc.publisher | WILEY-V C H VERLAG GMBH, BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY | en_US |
dc.subject | adhesion | en_US |
dc.subject | biological applications of polymers | en_US |
dc.subject | biomaterials; hydrogels | en_US |
dc.subject | tissue engineering | en_US |
dc.title | The Effect of Conjugating RGD into 3D Alginate Hydrogels on Adipogenic Differentiation of Human Adipose-Derived Stromal Cells | en_US |
dc.type | Article | en_US |
dc.relation.no | 5 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.1002/mabi.201000479 | - |
dc.relation.page | 673-679 | - |
dc.relation.journal | MACROMOLECULAR BIOSCIENCE | - |
dc.contributor.googleauthor | Kang, Sun-Woong | - |
dc.contributor.googleauthor | Cha, Byung-Hyun | - |
dc.contributor.googleauthor | Park, Honghyun | - |
dc.contributor.googleauthor | Park, Kwang-Sook | - |
dc.contributor.googleauthor | Lee, Kuen Yong | - |
dc.contributor.googleauthor | Lee, Soo-Hong | - |
dc.relation.code | 2011212230 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF ENGINEERING[S] | - |
dc.sector.department | DEPARTMENT OF BIOENGINEERING | - |
dc.identifier.pid | leeky | - |
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