Multifunctional Nanoparticles for Targeted Chemophotothermal Treatment of Cancer Cells
- Title
- Multifunctional Nanoparticles for Targeted Chemophotothermal Treatment of Cancer Cells
- Author
- 윤채옥
- Keywords
- cancer; chemophotothermal treatment; drug delivery; nanoparticles
- Issue Date
- 2011-08
- Publisher
- WILEY-V C H VERLAG GMBH, BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , 50, 33, 7581-7586
- Abstract
- Drug and heat delivery to tumors by active targeting with Herceptin-conjugated doxorubicin-loaded poly(ethylene glycol)?poly(lactic-co-glycolic acid)?Au half-shell nanoparticles (HER-DOX-PLGA-Au H-S NPs) is more effective than passive targeting with their HER-free counterparts (DOX-PLGA-Au H-S NPs). Thus, on NIR irradiation, higher intratumoral temperatures were reached in tumor-bearing mice that were treated with the HER-conjugated particles (see picture).
- URI
- http://onlinelibrary.wiley.com/doi/10.1002/anie.201101783/full
- ISSN
- 1433-7851
- DOI
- 10.1002/anie.201101783
- Appears in Collections:
- COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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