Tumor Size as a Prognostic Factor in Gastric Cancer Patient
- Title
- Tumor Size as a Prognostic Factor in Gastric Cancer Patient
- Author
- 김민규
- Keywords
- Gastric cancer; Prognosis; Tumor size
- Issue Date
- 2012-09
- Publisher
- 대한위암학회
- Citation
- Journal of gastric cancer,Vol.12 No.3 [2012],p164-172(9쪽)
- Abstract
- Purpose: The purpose of this study is to investigate the prognostic significance of tumor size for 5-year survival rate in patients with gastric cancer. Materials and Methods: A total of 1,697 patients with gastric cancer, who underwent potentially curative gastrectomy, were evaluated. Patients were divided into 4 groups as follows, according to the median size of early and advanced gastric cancer, respectively: small early gastric cancer (tumor size ≤3 cm), large early gastric cancer (tumor size >3 cm), small advanced gastric cancer (tumor size ≤ 6cm), and large advanced gastric cancer (tumor size >6 cm). The prognostic value of tumor size for 5-year survival rate was investigated. Results: In a univariate analysis, tumor size is a significant prognostic factor in advanced gastric cancer, but not in early gastric cancer. Multivariate analysis showed that tumor size is an independent prognostic factor for 5-year survival rate in advanced gastric cancer (P=0.003, hazard ratio=1.372, 95% confidence interval=1.115~1.690). When advanced gastric cancer is subdivided into 2 groups,according to serosa invasion: Group 1; serosa negative (T2 and T3, 7th AJCC), and Group 2; serosa positive (T4a and T4b, 7th AJCC),tumor size is an independent prognostic factor in Group 1 (P=0.011, hazard ratio=1.810, 95% confidence interval=1.149~2.852)and in Group 2 (P=0.033, hazard ratio=1.288, 95% confidence interval=1.020~1.627), respectively. Conclusions: Tumor size
- URI
- https://synapse.koreamed.org/DOIx.php?id=10.5230/jgc.2012.12.3.164http://hdl.handle.net/20.500.11754/39478
- ISSN
- 2093-582X; 2093-5641
- DOI
- 10.5230/jgc.2012.12.3.164
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
- jgc-12-164.pdfDownload
- Export
- RIS (EndNote)
- XLS (Excel)
- XML