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dc.contributor.author이영복-
dc.date.accessioned2018-02-17T09:07:44Z-
dc.date.available2018-02-17T09:07:44Z-
dc.date.issued2012-04-
dc.identifier.citationANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51, 21, 5179-5182en_US
dc.identifier.issn1433-7851-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/anie.201201003/abstract;jsessionid=DA604202EBFA59438994FCE7657ED10A.f04t03-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/37926-
dc.description.abstractProtein?mediated polarization transfer : Ligands L1 and L2 that competitively bind to a protein are subject to indirect spin?polarization transfer through the binding site of the protein. If protons H L1 of one ligand are hyperpolarized by dynamic nuclear polarization (DNP, see picture), signal intensities in the NMR spectrum of the second ligand become enhanced. The relative build?up of signal of the second ligand yields information on its binding epitope.en_US
dc.language.isoenen_US
dc.publisherWILEY-V C H VERLAG GMBH, PO BOX 10 11 61, D-69451 WEINHEIM, GERMANYen_US
dc.subjecthyperpolarizationen_US
dc.subjectligandsen_US
dc.subjectNMR spectroscopyen_US
dc.subjectproteinsen_US
dc.titleHyperpolarized Binding Pocket Nuclear Overhauser Effect for Determination of Competitive Ligand Bindingen_US
dc.typeArticleen_US
dc.relation.no21-
dc.relation.volume51-
dc.identifier.doi10.1002/anie.201201003-
dc.relation.page5179-5182-
dc.relation.journalANGEWANDTE CHEMIE-INTERNATIONAL EDITION-
dc.contributor.googleauthorLee, Youngbok-
dc.contributor.googleauthorZeng, Haifeng-
dc.contributor.googleauthorMazur, Adam-
dc.contributor.googleauthorWegstroth, Melanie-
dc.contributor.googleauthorCarlomagno, Teresa-
dc.contributor.googleauthorReese, Marcel-
dc.contributor.googleauthorLee, Donghan-
dc.contributor.googleauthorBecker, Stefan-
dc.contributor.googleauthorGriesinger, Christian-
dc.contributor.googleauthorHilty, Christian-
dc.relation.code2012200613-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidyblee-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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