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dc.contributor.author황승용-
dc.date.accessioned2018-02-13T02:26:51Z-
dc.date.available2018-02-13T02:26:51Z-
dc.date.issued2011-09-
dc.identifier.citationBIOCHIP JOURNAL, Vol.5, No.3 [2011], p255-264en_US
dc.identifier.issn1976-0280-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/j.1399-0039.2005.00395.x/abstract-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/36999-
dc.description.abstractHuman Leukocyte Antigen (HLA), called human Major Histocompatibility Complex (MHC), performs the crucial function of antigen presentation in human immunity, and correctly matched HLA antigens improves survival and reduces immunological complications. Therefore, a precise HLA typing method is necessary for successful transplantation between donor and recipient. Until now, many methods have been developed for HLA typing, including serological and DNA-based methods. However, these previous methods have been somewhat limited due to their requirements for a large number of samples and complex experimental procedures. To resolve this problem, in this study, we developed rapid genotyping methods for HLA-C using an oligonucleotide microarray. To evaluate the performance of the HLA-C genotyping microarray, we analyzed 50 unrelated Korean individuals. The genotyping results obtained by the oligonucleotide microarray were identical with those of PCR-SBT and PCR-SSPs, at a low-resolution, 2-digit level. Therefore, this microarray method for genotyping HLA constitutes a rapid, simultaneous, and high-throughput method that can be used as an alternative to current methods.en_US
dc.language.isoenen_US
dc.publisherKOREAN BIOCHIP SOCIETY-KBCS, KOREA SCI & TECHNOL CENT, #310, 635-4, YEOGSAM-DONG, KANGNAM-GU, SEOUL, 135-703, SOUTH KOREAen_US
dc.subjectHLAen_US
dc.subjectHLA-C genotypingen_US
dc.subjectMicroarrayen_US
dc.subjectDNA chipen_US
dc.subjectTransplantationen_US
dc.subjectSTEM-CELL TRANSPLANTATIONen_US
dc.subjectCLASS-Ien_US
dc.subjectANKYLOSING-SPONDYLITISen_US
dc.subjectMARROW-TRANSPLANTATIONen_US
dc.subjectRENAL-TRANSPLANTATIONen_US
dc.subjectAUTOIMMUNE HEPATITISen_US
dc.subjectCLINICAL-EVALUATIONen_US
dc.subjectPCR AMPLIFICATIONen_US
dc.subjectUNRELATED DONORSen_US
dc.subjectACUTE REJECTIONen_US
dc.titleDevelopment of simple and rapid HLA-C genotyping method using an oligonucleotide microarrayen_US
dc.typeArticleen_US
dc.relation.no3-
dc.relation.volume5-
dc.identifier.doi10.1007/s13206-011-5310-1-
dc.relation.page255-264-
dc.relation.journalBIOCHIP JOURNAL-
dc.contributor.googleauthorKim, Hee-Jin-
dc.contributor.googleauthorYoon, Hyun-Kyu-
dc.contributor.googleauthorChung, In-Hyuk-
dc.contributor.googleauthorHwang, Seung-Yong-
dc.contributor.googleauthorKim, Jun-Sub-
dc.contributor.googleauthorKim, Hee-Jin-
dc.contributor.googleauthorLee, Ki-O-
dc.contributor.googleauthorPark, Eui-Jin-
dc.contributor.googleauthorSong, Sang-Yong-
dc.contributor.googleauthorBang, Sa-Ik-
dc.contributor.googleauthorKim, Tae-Sung-
dc.relation.code2011217720-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidsyhwang-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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