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Presenting multiple adhesion ligands on hydrogels for control of PC12 phenotype

Title
Presenting multiple adhesion ligands on hydrogels for control of PC12 phenotype
Author
이근용
Keywords
Adrenal Gland Neoplasms, metabolism; pathology; Alginates; chemistry; Animals; Biomarkers; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; GAP-43 Protein
Issue Date
2011-11
Publisher
Medline
Citation
Journal of Controlled Release, Nov 2011, P219-220
Abstract
ABSTRACT SUMMARY: Peptides with the sequence of RGD and YIGSR have been frequently used to regulate many critical aspects of cell adhesion, proliferation, and differentiation. We demonstrated that the presence of both RGD and YIGSR peptides in alginate gels showed a synergistic effect on adhesion, proliferation, and differentiation of PC12 cells in vitro. Hydrogels modified with multiple adhesion peptides could find useful applications in tissue engineering.
URI
https://www.sciencedirect.com/science/article/pii/S0168365911008066?via%3Dihubhttp://hdl.handle.net/20.500.11754/36985
ISSN
0168-3659
DOI
10.1016/j.jconrel.2011.09.021
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > BIOENGINEERING(생명공학과) > Articles
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