Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤호주 | - |
dc.date.accessioned | 2018-02-07T04:24:28Z | - |
dc.date.available | 2018-02-07T04:24:28Z | - |
dc.date.issued | 2011-12 | - |
dc.identifier.citation | Tuberculosis and Respiratory Diseases, 2011, 71(6), P.425-430(6) | en_US |
dc.identifier.issn | 0378-0066 | - |
dc.identifier.uri | https://synapse.koreamed.org/DOIx.php?id=10.4046/trd.2011.71.6.425 | - |
dc.description.abstract | Background: High 2-[$^{18}F$] fluoro-2-deoxy-D-glucose (FDG) uptake on positron emission tomography-computed tomography (PET-CT) is a prognostic factor for poor survival in non-small cell lung cancer (NSCLC), especially in Stage I. We determined whether the high FDG uptake value of a primary tumor was associated with recurrence and death in patients with resected Stage I and Stage II NSCLC. Methods: We identified consecutive patients who underwent complete surgical resection for Stage I and II NSCLC between 2006 and 2009, who had preoperative PET-CT, and reviewed clinical records retrospectively. FDG uptake was measured as the maximal standardized uptake value (SUVmax) for body weight. Patients were divided into two groups based on SUVmax: (i) above or (ii) below the cut-off value (SUVmax=5.9) determined by a receiver operating characteristic (ROC) curve. Results: Of 57 patients who were enrolled consecutively, 32 (56%) had Stage I NSCLC and 25 (44%) had Stage II. The 5-year recurrence-free survival (RFS) for patients with high (${\geq}5.9$) and low (<5.9) SUVmax were 31% and 57%, respectively (p=0.014). The 5-year overall survival (OS) rates were 39% and 60%, respectively (p=0.029). In univariate analyses, SUVmax (p=0.014), T staging (p=0.025), and differentiation of tumor tissue (p=0.034) were significantly associated with RFS. But, multivariate analyses did not show that SUVmax was an independently significant factor for RFS (p=0.180). Conclusion: High FDG uptake on PET-CT is not an independent prognostic factor for poor outcomes (disease recurrence in patients with resected Stage I and II NSCLC). | en_US |
dc.language.iso | ko_KR | en_US |
dc.publisher | 대한결핵및호흡기학회 | en_US |
dc.subject | Carcinoma, Non-Small Cell Lung | en_US |
dc.subject | Positron-Emission Tomography | en_US |
dc.subject | Prognosis | en_US |
dc.title | I, II병기 비소세포폐암의 예후에 대한 수술 전 양전자방출 컴퓨터 단층촬영기 의 임상적 의의 | en_US |
dc.title.alternative | Prognostic Value of Preoperative Positron Emission Tomography-Computed Tomography in Surgically Resected Stage I and II Non-Small Cell Lung Cancer | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 71 | - |
dc.identifier.doi | 10.4046/trd.2011.71.6.425 | - |
dc.relation.page | 425-430 | - |
dc.relation.journal | Tuberculosis and Respiratory Diseases | - |
dc.contributor.googleauthor | 송성헌 | - |
dc.contributor.googleauthor | 손장원 | - |
dc.contributor.googleauthor | 곽현정 | - |
dc.contributor.googleauthor | 김사일 | - |
dc.contributor.googleauthor | 김상헌 | - |
dc.contributor.googleauthor | 김태형 | - |
dc.contributor.googleauthor | 윤호주 | - |
dc.contributor.googleauthor | 신동호 | - |
dc.contributor.googleauthor | 최윤영 | - |
dc.contributor.googleauthor | 박성수 | - |
dc.contributor.googleauthor | Song, Sung-Heon | - |
dc.contributor.googleauthor | Sohn, Jang-Won | - |
dc.contributor.googleauthor | Kwak, Hyun-Jung | - |
dc.contributor.googleauthor | Kim, Sa-Il | - |
dc.contributor.googleauthor | Kim, Sang-Heon | - |
dc.contributor.googleauthor | Kim, Tae-Hyung | - |
dc.contributor.googleauthor | Yoon, Ho-Joo | - |
dc.contributor.googleauthor | Shin, Dong-Ho | - |
dc.contributor.googleauthor | Choi, Yoon-Young | - |
dc.contributor.googleauthor | Park, Sung-Soo | - |
dc.relation.code | 2012230388 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | hjyoon | - |
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