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dc.contributor.author이찬길-
dc.date.accessioned2018-02-06T05:28:24Z-
dc.date.available2018-02-06T05:28:24Z-
dc.date.issued2015-03-
dc.identifier.citationJOURNAL OF HAZARDOUS MATERIALS, v. 285, Page. 11-17en_US
dc.identifier.issn0304-3894-
dc.identifier.issn1873-3336-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0304389414009182-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/35589-
dc.description.abstract"Aflatoxin B1 (AFB1) is a well-known carcinogenic contaminant in foods. It is classified as an extremely hazardous compound because of its potential toxicity to the human nervous system. AFB1 has also been extensively used as a biochemical marker to evaluate the degree of food spoilage. In this study, a novel surface-enhanced Raman scattering (SERS)-based immunoassay platform using silica-encapsulated hollow gold nanoparticles (SEHGNs) and magnetic beads was developed for highly sensitive detection of AFB1.SEHGNs were used as highly stable SERS-encoding nano tags, and magnetic beads were used as supporting substrates for the high-density loading of immunocomplexes. Quantitative analysis of AFB1 was performed by monitoring the intensity change of the characteristic peaks of Raman reporter molecules. The limit of detection (LOD) of AFB1, determined by this SERS-based immunoassay, was determined to be 0.1 ng/mL. This method has some advantages over other analytical methods with respect to rapid analysis (less than 30 min), good selectivity, and reproducibility. The proposed method is expected to be a new analytical tool for the trace analysis of various mycotoxins. (C) 2014 Elsevier B.V. All rights reserved."en_US
dc.description.sponsorshipThis work was supported by the National Research Foundation of Korea (grant number K20904000004-13A0500-00410). This research was also supported by the BioNano Health-Guard Research Center funded by the Ministry of Science, ICT and Future Planning of Korea as the Global Frontier Project (grant number 2013M3A6B2078957).en_US
dc.language.isoen_USen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.subjectAflatoxin B1en_US
dc.subjectMycotoxinen_US
dc.subjectSurface-enhanced Raman scatteringen_US
dc.subjectSilica-encapsulationen_US
dc.subjectMagnetic beaden_US
dc.subjectENHANCED RAMAN-SCATTERINGen_US
dc.subjectRAPID DETECTIONen_US
dc.subjectMYCOTOXINSen_US
dc.subjectCONTAMINATIONen_US
dc.subjectNANOSPHERESen_US
dc.subjectNANOPROBESen_US
dc.subjectANTIGENen_US
dc.subjectMARKERSen_US
dc.subjectHEALTHen_US
dc.subjectSENSORen_US
dc.titleHighly sensitive SERS-based immunoassay of aflatoxin B1 using silica-encapsulated hollow gold nanoparticlesen_US
dc.typeArticleen_US
dc.relation.volume285-
dc.identifier.doi10.1016/j.jhazmat.2014.11.018-
dc.relation.page11-17-
dc.relation.journalJOURNAL OF HAZARDOUS MATERIALS-
dc.contributor.googleauthorKo, Juhui-
dc.contributor.googleauthorLee, Chankil-
dc.contributor.googleauthorChoo, Jaebum-
dc.relation.code2015000315-
dc.sector.campusE-
dc.sector.daehakCOLLEGE OF ENGINEERING SCIENCES[E]-
dc.sector.departmentDIVISION OF ELECTRICAL ENGINEERING-
dc.identifier.pidcklee-
Appears in Collections:
COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > ELECTRICAL ENGINEERING(전자공학부) > Articles
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