Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 류재숙 | - |
dc.date.accessioned | 2018-02-03T06:35:10Z | - |
dc.date.available | 2018-02-03T06:35:10Z | - |
dc.date.issued | 2011-03 | - |
dc.identifier.citation | Korean Journal of Parasitology, 2011, 49(1), P.79-83 | en_US |
dc.identifier.issn | 0023-4001 | - |
dc.identifier.issn | 1738-0006 | - |
dc.identifier.uri | http://parasitol.kr/journal/view.php?doi=10.3347/kjp.2011.49.1.79 | - |
dc.description.abstract | Trichomoniasis is a sexually transmitted disease due to infection with Trichomonas vaginalis, and it can cause serious consequences for women's health. To study the virulence factors of this pathogen, T vaginalis surface proteins were investigated using polyclonal antibodies specific to the membrane fractions of T vaginalis. The T vaginalis expression library was constructed by cloning the cDNA derived from mRNA of T vaginalis into a phage lambda Uni-ZAP XR vector, and then used for immunoscreening with the anti-membrane proteins of T. vaginalis antibodies. The immunoreactive proteins identified included adhesion protein AP65-1, alpha-actinin, kinesin-associated protein, teneurin, and 2 independent hypothetical proteins. Immunofluorescence assays showed that AP65-1, one of the identified immunogenic clones, is prevalent in the whole body of T vaginalis. This study led us to identify T vaginalis proteins which may stimulate immune responses by human cells. | en_US |
dc.description.sponsorship | This work was supported by the Korean Research Foundation Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund) (KRF-2007-314-E00070). This work was partially supported by the Seoul R&BD Program (grant 10580), Korea. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Korean SOC Parasitology | en_US |
dc.subject | Trichomonas vaginalis | en_US |
dc.subject | antigenic protein | en_US |
dc.subject | membrane protein | en_US |
dc.subject | immunoscreening | en_US |
dc.title | Identification of Antigenic Proteins in Trichomonas vaginalis | en_US |
dc.type | Article | en_US |
dc.relation.no | 1 | - |
dc.relation.volume | 49 | - |
dc.identifier.doi | 10.3347/kjp.2011.49.1.79 | - |
dc.relation.page | 79-83 | - |
dc.relation.journal | KOREAN JOURNAL OF PARASITOLOGY | - |
dc.contributor.googleauthor | Lee, Hye-Yeon | - |
dc.contributor.googleauthor | Hyung, Sujin | - |
dc.contributor.googleauthor | Lee, Jong Woong | - |
dc.contributor.googleauthor | Kim, Juri | - |
dc.contributor.googleauthor | Shin, Myeong Heon | - |
dc.contributor.googleauthor | Ryu, Jae-Sook | - |
dc.contributor.googleauthor | Park, Soon-Jung | - |
dc.relation.code | 2011217609 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | jsryu | - |
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