Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 주재범 | - |
dc.date.accessioned | 2018-02-02T06:43:19Z | - |
dc.date.available | 2018-02-02T06:43:19Z | - |
dc.date.issued | 2011-04 | - |
dc.identifier.citation | ANALYTICAL CHEMISTRY, v. 83, NO. 8, Page. 3076-3081 | en_US |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.uri | https://pubs.acs.org/doi/abs/10.1021/ac103329b | - |
dc.description.abstract | The development of ultrafast Raman-based detection is one of the most interesting challenges underpinning the application of droplet based microfluidics. Herein, we describe the use of surface-enhanced resonance Raman spectroscopy (SERRS) with submillisecond time resolution as a powerful detection tool in microdroplet reactors. Individual droplets containing silver nanoparticle aggregates functionalized with Raman reporters are interrogated and characterized by full spectra acquisitions with high spatial resolution in real time. Whereas previous works coupling SERRS with droplet-based microfluidics acquire a single spectrum over single or multiple droplets, we build upon these results by increasing our temporal resolution by 2 orders of magnitude. This allows us to interrogate multiple points within one individual droplet. The SERRS signals emitted from the aggregates are utilized to access the influence of flow rate on droplet size and throughput. Accordingly, our approach allows for high-throughput analysis that facilitates the study of other biological assays or molecular interactions. | en_US |
dc.description.sponsorship | M.P.C. and J.H. contributed equally to this work. This work was supported by the RCUK Microdroplets Basic Technology Project. The authors also acknowledge the National Research Foundation of Korea (Grant Numbers R11-2009-044-1002-0K20904000004-09A050000410). J.H. acknowledges the Brain Korea 21 Project. The authors acknowledge Prof. David McComb for his useful discussion. M.P.C. and J.H. contributed equally toward this publication. | en_US |
dc.language.iso | en | en_US |
dc.publisher | AMER CHEMICAL SOC | en_US |
dc.subject | ELECTROCHEMICAL DETECTION | en_US |
dc.subject | TRIPHENYLMETHANE DYES | en_US |
dc.subject | LATEST DEVELOPMENTS | en_US |
dc.subject | MALACHITE GREEN | en_US |
dc.subject | MICRODROPLETS | en_US |
dc.subject | NANOPARTICLES | en_US |
dc.subject | GENERATION | en_US |
dc.subject | KINETICS | en_US |
dc.subject | MICRO | en_US |
dc.title | Ultrafast Surface Enhanced Resonance Raman Scattering Detection in Droplet-Based Microfluidic Systems | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 83 | - |
dc.identifier.doi | 10.1021/ac103329b | - |
dc.relation.page | 3076-3081 | - |
dc.relation.journal | ANALYTICAL CHEMISTRY | - |
dc.contributor.googleauthor | Cecchini, MP | - |
dc.contributor.googleauthor | Hong, J | - |
dc.contributor.googleauthor | Lim, C | - |
dc.contributor.googleauthor | Choo, J | - |
dc.contributor.googleauthor | Albrecht, T | - |
dc.contributor.googleauthor | Demello, AJ | - |
dc.contributor.googleauthor | Edel, JB | - |
dc.relation.code | 2011200599 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | jbchoo | - |
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