Neurogenesis in Stroke Recovery
- Title
- Neurogenesis in Stroke Recovery
- Author
- 박현희
- Keywords
- Stroke; Neurogenesis; Neural stem cells
- Issue Date
- 2016-03
- Publisher
- SPRINGER
- Citation
- TRANSLATIONAL STROKE RESEARCH, v. 8, NO 1, Page. 3-13
- Abstract
- Stroke, resulting from limited blood flow to the brain, is one of the most important causes of morbidity and mortality worldwide. Stroke is classified as ischemic, due to lack of blood flow, or hemorrhagic, due to bleeding. Because 87 % of strokes are classified as ischemic, this type will be the predominant focus of this review. Except for thrombolytic therapy, there is no established treatment to reduce the neurological deficits caused by ischemic stroke. Therefore, it is necessary to develop new therapeutic strategies designed to improve neurological functions after ischemic stroke. Recently, therapies to enhance neurogenesis after ischemic stroke have been investigated. However, these approaches have not led to successful clinical outcomes. This review addresses the pathophysiology of stroke, neurogenesis after stroke, and how to stimulate these processes based on the current literature. Finally, ongoing clinical trials to improve neurological functions after stroke by enhancing neurogenesis are discussed in this review.
- URI
- https://link.springer.com/article/10.1007%2Fs12975-016-0460-zhttp://hdl.handle.net/20.500.11754/34562
- ISSN
- 1868-4483; 1868-601X
- DOI
- 10.1007/s12975-016-0460-z
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML