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Nanoparticles for Use in Enzyme Assays

Title
Nanoparticles for Use in Enzyme Assays
Author
김영필
Keywords
biosensors; enzyme assays; gold; magnetic nanoparticles; nanoparticles; quantum dots
Issue Date
2016-02
Publisher
WILEY-V C H VERLAG GMBH
Citation
CHEMBIOCHEM, v. 17, NO 4, Page. 275-282
Abstract
Nanoparticles (NPs) have created new ways to enhance the performance of classical biosensors in analytical sciences. NPs with unprecedented physiochemical properties can serve both as excellent carriers of bioreceptors and as signal enhancers, leading to improved assay platforms with high sensitivity and selectivity. Because enzymes play central roles in many cellular functions, specific and precise assays of their functions are of great significance in medical science and biotechnology. Here we review recent advances in NP-based biosensors and their use in enzyme assays. With fast and specific responses to enzyme-mediated reactions, NPs transduce and amplify the initial responses into various types of signals, such as electrochemical, optical and magnetic ones. Translation of their potential should lead to functionalized NPs finding wide applications in diagnostics, drug development and biotechnology.
URI
http://onlinelibrary.wiley.com/doi/10.1002/cbic.201500512/fullhttp://hdl.handle.net/20.500.11754/33849
ISSN
1439-4227; 1439-7633
DOI
10.1002/cbic.201500512
Appears in Collections:
COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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