Nanoparticles for Use in Enzyme Assays
- Title
- Nanoparticles for Use in Enzyme Assays
- Author
- 김영필
- Keywords
- biosensors; enzyme assays; gold; magnetic nanoparticles; nanoparticles; quantum dots
- Issue Date
- 2016-02
- Publisher
- WILEY-V C H VERLAG GMBH
- Citation
- CHEMBIOCHEM, v. 17, NO 4, Page. 275-282
- Abstract
- Nanoparticles (NPs) have created new ways to enhance the performance of classical biosensors in analytical sciences. NPs with unprecedented physiochemical properties can serve both as excellent carriers of bioreceptors and as signal enhancers, leading to improved assay platforms with high sensitivity and selectivity. Because enzymes play central roles in many cellular functions, specific and precise assays of their functions are of great significance in medical science and biotechnology. Here we review recent advances in NP-based biosensors and their use in enzyme assays. With fast and specific responses to enzyme-mediated reactions, NPs transduce and amplify the initial responses into various types of signals, such as electrochemical, optical and magnetic ones. Translation of their potential should lead to functionalized NPs finding wide applications in diagnostics, drug development and biotechnology.
- URI
- http://onlinelibrary.wiley.com/doi/10.1002/cbic.201500512/fullhttp://hdl.handle.net/20.500.11754/33849
- ISSN
- 1439-4227; 1439-7633
- DOI
- 10.1002/cbic.201500512
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML