Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오영하 | - |
dc.date.accessioned | 2017-11-22T07:33:33Z | - |
dc.date.available | 2017-11-22T07:33:33Z | - |
dc.date.issued | 2016-02 | - |
dc.identifier.citation | ONCOLOGY LETTERS, v. 11, NO 4, Page. 2861-2864 | en_US |
dc.identifier.issn | 1792-1074 | - |
dc.identifier.issn | 1792-1082 | - |
dc.identifier.uri | https://www.spandidos-publications.com/10.3892/ol.2016.4286 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/31773 | - |
dc.description.abstract | Oxaliplatin is an effective chemotherapeutic agent for the treatment of colorectal cancer; however, it may cause liver injury, particularly sinusoidal obstruction syndrome (SOS). Although SOS does not usually present with focal lesions on radiological images, the present study describes the case of a 22-year-old woman with oxaliplatin-induced SOS mimicking metastatic colon cancer in the liver. An abdominal computed tomography revealed a novel 1 cm, low-density lesion in segment 1 of the liver following the administration of the fourth round of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer. Since the lesion was indistinguishable from metastasis, even with detailed imaging studies, including magnetic resonance imaging and positron emission tomography-computed tomography, an isolated caudate lobectomy was planned. The cut surface of the resected liver showed a localized reddish congested lesion measuring 1.4 cm in diameter. The adjacent hepatic parenchyma also demonstrated diffuse sinusoidal congestion with a nutmeg-like appearance. Histologically, the lesion exhibited severe sinusoidal congestion with peliosis hepatis-like features. The widened sinusoidal space was outlined by markedly attenuated hepatic cords and filled with erythrocytes. The final diagnosis was oxaliplatin-induced SOS. The patient recovered completely and was relapse-free at the time of writing. | en_US |
dc.language.iso | en | en_US |
dc.publisher | SPANDIDOS PUBL LTD | en_US |
dc.subject | oxaliplatin | en_US |
dc.subject | sinusoidal obstruction syndrome | en_US |
dc.subject | colon cancer | en_US |
dc.title | Oxaliplatin-induced sinusoidal obstruction syndrome mimicking metastatic colon cancer in the liver | en_US |
dc.type | Article | en_US |
dc.relation.no | 4 | - |
dc.relation.volume | 11 | - |
dc.identifier.doi | 10.3892/ol.2016.4286 | - |
dc.relation.page | 2861-2864 | - |
dc.relation.journal | ONCOLOGY LETTERS | - |
dc.contributor.googleauthor | Choi, Jung-Hye | - |
dc.contributor.googleauthor | Won, Young-Woong | - |
dc.contributor.googleauthor | Kim, Hyun Sung | - |
dc.contributor.googleauthor | Oh, Young-Ha | - |
dc.contributor.googleauthor | Lim, Sanghyeok | - |
dc.contributor.googleauthor | Kim, Han-Joon | - |
dc.relation.code | 2016004702 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | yhoh | - |
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