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VARIABILITY IN INTERPRETATION OF ULTRASOUND ELASTOGRAPHY AND GRAY-SCALE ULTRASOUND IN ASSESSING THYROID NODULES

Title
VARIABILITY IN INTERPRETATION OF ULTRASOUND ELASTOGRAPHY AND GRAY-SCALE ULTRASOUND IN ASSESSING THYROID NODULES
Author
박정선
Keywords
Elastography; Thyroid nodule; Inter-observer variability; Ultrasound; Diagnosis
Issue Date
2016-01
Publisher
ELSEVIER SCIENCE INC
Citation
ULTRASOUND IN MEDICINE AND BIOLOGY, v. 42, NO 1, Page. 51-59
Abstract
The aim of this study was to validate inter-observer variability for strain ultrasound elastography (USE) and to compare the diagnostic performance of a combination of gray-scale ultrasound (US) and USE with that of gray-scale US. Three observers from different institutions evaluated gray-scale US images and USE video files of 443 cytopathologically proven benign or malignant thyroid nodules over a 3-mo period. Interobserver variability did not statistically differ between USE using the Asteria criteria and gray-scale US; however, USE using the Rago criteria had the lowest inter-observer agreement (p < 0.043). For all three observers, sensitivity was increased by adding USE to gray-scale US (81.3%-88.3%, 75.4%-85.4%) compared with gray-scale US (70.4%-80.8%). Specificity was decreased by adding USE to gray-scale US (51.7%-59.1%, 59.1%-73.9%) compared with gray-scale US (69.0%-82.8%). USE and gray-scale US had comparable inter-observer variability. However, on addition of USE to gray-scale US, the additional diagnostic yield was limited compared with that of gray-scale US alone. (C) 2016 World Federation for Ultrasound in Medicine & Biology.
URI
http://www.sciencedirect.com/science/article/pii/S0301562915004871?via%3Dihubhttp://hdl.handle.net/20.500.11754/31696
ISSN
0301-5629; 1879-291X
DOI
10.1016/j.ultrasmedbio.2015.08.005
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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