174 0

Increased white matter connectivity in traumatized children with attention deficit hyperactivity disorder

Title
Increased white matter connectivity in traumatized children with attention deficit hyperactivity disorder
Author
이종민
Keywords
Attention-deficit hyperactivity disorder; Trauma; Diffusion tensor imaging
Issue Date
2016-01
Publisher
ELSEVIER IRELAND LTD
Citation
PSYCHIATRY RESEARCH-NEUROIMAGING, v. 247, Page. 57-63
Abstract
To distinguish between the consequences of trauma exposure and those of attention deficit hyperactivity disorder (ADHD), we compared brain diffusion tensor imaging (DTI) of children according to the diagnosis and the presence of a potentially traumatic event (PTE). The Early Trauma Inventory Self ReportShort Form (ETISR-SF) was used for the assessment of PTEs. Subjects who experienced any traumatic event were placed in the PTE group, and subjects who did not experience such a traumatic event were placed in the non-PTE group. We examined the interactions between ADHD and PTEs in brain [fractional anisotropy (FA) values and mean diffusivity (MD) values] in 54 children with ADHD (29 with PTEs and 25 without PTEs) and 41 controls (18 with PTEs and 23 without PTEs). Analysis of covariance (ANCOVA) revealed main effects of ADHD for FA and MD values in several white matter tracts in the absence of main effects for PTEs. In addition, there was a significant ADHD-PTEs interaction in relation to FA and MD values in several white matter tracts. Further longitudinal studies in a larger sample are warranted to evaluate the neurobiological sequelae related to childhood trauma, ADHD, and interaction between the two. (C) 2015 Published by Elsevier Ireland Ltd.
URI
http://www.sciencedirect.com/science/article/pii/S0925492715300895?via%3Dihubhttp://hdl.handle.net/20.500.11754/31469
ISSN
0925-4927; 1872-7506
DOI
10.1016/j.pscychresns.2015.09.012
Appears in Collections:
COLLEGE OF ENGINEERING[S](공과대학) > ELECTRICAL AND BIOMEDICAL ENGINEERING(전기·생체공학부) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE