Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김희태 | - |
dc.date.accessioned | 2017-11-09T04:50:23Z | - |
dc.date.available | 2017-11-09T04:50:23Z | - |
dc.date.issued | 2016-01 | - |
dc.identifier.citation | NEURODEGENERATIVE DISEASES, v. 16, NO 3-4, Page. 199-205 | en_US |
dc.identifier.issn | 1660-2854 | - |
dc.identifier.issn | 1660-2862 | - |
dc.identifier.uri | https://www.karger.com/Article/FullText/441917 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/30600 | - |
dc.description.abstract | Background and Objectives: Gastrointestinal dysfunction is a common non motor symptom in Parkinson's disease (PD). However, the potential association between vitamin D and gastroparesis in PD has not been previously investigated. The aim of this study was to compare vitamin D levels between drug-naive de novo PD patients with normal gastric emptying and those with delayed gastric emptying. Methods: Fifty-one patients with drug-naive de novo PD and 20 age-matched healthy controls were enrolled in this study. Gastric emptying time (GET) was assessed by scintigraphy, and gastric emptying half-time (T-1/2) was determined. The PD patients were divided into a delayed-GET group and a normal-GET group. Results: The serum 25-hydroxyvitamin D-3 levels were decreased in the delayed-GET group compared with the normal-GET and control groups (11.59 +/- 4.90 vs. 19.43 +/- 6.91 and 32.69 +/- 4.93, respectively, p ˂ 0.01). In the multivariate model, the serum 25-hydroxyvitamin D-3 level was independently associated with delayed gastric emptying in PD patients. Conclusions: Vitamin D status may be an independent factor for gastric dysmotility in PD. Although the underlying mechanism remains to be characterized, vitamin D status may play a role in the pathogenesis of delayed gastric emptying in drug-naive PD. (C) 2016 S. Karger AG, Basel | en_US |
dc.description.sponsorship | This work was funded by the Gangneung Asan Hospital Biomedical Research Centre Promotion Fund. | en_US |
dc.language.iso | en | en_US |
dc.publisher | KARGER | en_US |
dc.subject | 25-Hydroxyvitamin D-3 | en_US |
dc.subject | Gastric emptying time | en_US |
dc.subject | Parkinson's disease | en_US |
dc.subject | Vitamin D | en_US |
dc.title | Low Serum Vitamin D Levels May Contribute to Gastric Dysmotility in de novo Parkinson's Disease | en_US |
dc.type | Article | en_US |
dc.relation.no | 3-4 | - |
dc.relation.volume | 16 | - |
dc.identifier.doi | 10.1159/000441917 | - |
dc.relation.page | 199-205 | - |
dc.relation.journal | NEURODEGENERATIVE DISEASES | - |
dc.contributor.googleauthor | Kwon, Ki Young | - |
dc.contributor.googleauthor | Jo, Kwang Deog | - |
dc.contributor.googleauthor | Lee, Moon Kyu | - |
dc.contributor.googleauthor | Oh, Minyoung | - |
dc.contributor.googleauthor | Kim, Eyu Nyong | - |
dc.contributor.googleauthor | Park, Jinse | - |
dc.contributor.googleauthor | Kim, Ji Sun | - |
dc.contributor.googleauthor | Youn, Jinyoung | - |
dc.contributor.googleauthor | Oh, Engseok | - |
dc.contributor.googleauthor | Kim, Hee-Tae | - |
dc.relation.code | 2016007848 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | kimht | - |
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