Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이수재 | - |
dc.date.accessioned | 2017-10-24T02:36:22Z | - |
dc.date.available | 2017-10-24T02:36:22Z | - |
dc.date.issued | 2015-12 | - |
dc.identifier.citation | MOLECULAR AND CELLULAR PROBES, v. 29, NO 6, Page. 492-499 | en_US |
dc.identifier.issn | 0890-8508 | - |
dc.identifier.uri | http://www.sciencedirect.com/science/article/pii/S0890850815300104?via%3Dihub | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/30221 | - |
dc.description.abstract | Metastasis and recurrence of breast cancer remain significant clinical problems. The expression level of CD44 protein is higher in breast cancer-initiating cancer stem cells; therefore, the early detection of CD44 using a sensitive diagnostic probe is important for breast cancer diagnosis and therapeutic purposes. In this study, we fabricated a polyvalent directed peptide polymer (PDPP) that specifically recognized the CD44 biomarker, as confirmed by immunocytochemistry tests and fluorescence-activated cell sorting assessment. Our results indicate that PDPP is useful as a novel tool for the sensitive detection of breast cancer stem cells. (C) 2015 Elsevier Ltd. All rights reserved. | en_US |
dc.description.sponsorship | This research was supported by the Converging Research Center Program funded by the Ministry of Science, ICT & Future Planning (Project No. 2014048814). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD | en_US |
dc.subject | CD44 | en_US |
dc.subject | Breast cancer stem cell | en_US |
dc.subject | Peptide | en_US |
dc.subject | PDPP | en_US |
dc.title | A novel peptide-based recognition probe for the sensitive detection of CD44 on breast cancer stem cells | en_US |
dc.type | Article | en_US |
dc.relation.no | 6 | - |
dc.relation.volume | 29 | - |
dc.identifier.doi | 10.1016/j.mcp.2015.05.014 | - |
dc.relation.page | 492-499 | - |
dc.relation.journal | MOLECULAR AND CELLULAR PROBES | - |
dc.contributor.googleauthor | Cho, Jun-Haeng | - |
dc.contributor.googleauthor | Lee, Sang-Choon | - |
dc.contributor.googleauthor | Ha, Na-Reum | - |
dc.contributor.googleauthor | Lee, Su-Jae | - |
dc.contributor.googleauthor | Yoon, Moon-Young | - |
dc.relation.code | 2015001286 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF NATURAL SCIENCES[S] | - |
dc.sector.department | DEPARTMENT OF LIFE SCIENCE | - |
dc.identifier.pid | sj0420 | - |
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