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dc.contributor.author윤문영-
dc.date.accessioned2017-10-18T08:18:52Z-
dc.date.available2017-10-18T08:18:52Z-
dc.date.issued2015-12-
dc.identifier.citationMOLECULAR AND CELLULAR PROBES, v. 29, NO 6, Page. 492-499en_US
dc.identifier.issn0890-8508-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0890850815300104?via%3Dihub-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/30097-
dc.description.abstractMetastasis and recurrence of breast cancer remain significant clinical problems. The expression level of CD44 protein is higher in breast cancer-initiating cancer stem cells; therefore, the early detection of CD44 using a sensitive diagnostic probe is important for breast cancer diagnosis and therapeutic purposes. In this study, we fabricated a polyvalent directed peptide polymer (PDPP) that specifically recognized the CD44 biomarker, as confirmed by immunocytochemistry tests and fluorescence-activated cell sorting assessment. Our results indicate that PDPP is useful as a novel tool for the sensitive detection of breast cancer stem cells. (C) 2015 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipThis research was supported by the Converging Research Center Program funded by the Ministry of Science, ICT & Future Planning (Project No. 2014048814).en_US
dc.language.isoenen_US
dc.publisherACADEMIC PRESS LTD- ELSEVIER SCIENCE LTDen_US
dc.subjectCD44en_US
dc.subjectBreast cancer stem cellen_US
dc.subjectPeptideen_US
dc.subjectPDPPen_US
dc.titleA novel peptide-based recognition probe for the sensitive detection of CD44 on breast cancer stem cellsen_US
dc.typeArticleen_US
dc.relation.no6-
dc.relation.volume29-
dc.identifier.doi10.1016/j.mcp.2015.05.014-
dc.relation.page492-499-
dc.relation.journalMOLECULAR AND CELLULAR PROBES-
dc.contributor.googleauthorCho, Jun-Haeng-
dc.contributor.googleauthorLee, Sang-Choon-
dc.contributor.googleauthorHa, Na-Reum-
dc.contributor.googleauthorLee, Su-Jae-
dc.contributor.googleauthorYoon, Moon-Young-
dc.relation.code2015001286-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF NATURAL SCIENCES[S]-
dc.sector.departmentDEPARTMENT OF CHEMISTRY-
dc.identifier.pidmyyoon-
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COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > CHEMISTRY(화학과) > Articles
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