261 108

The current status of directed differentiation technology

Title
The current status of directed differentiation technology
Author
최동호
Keywords
Cell Differentiation; Cellular Reprogramming; Transcription Factors; Regenerative Medicine
Issue Date
2015-12
Publisher
한양대학교 의과대학
Citation
Hanyang Medical Reviews, v. 35, NO 4, Page. 215-221
Abstract
The direct reprogramming of a terminally differentiated cell into another lineage using defined combinations of factors has fundamentally changed traditional concepts of the inalterability of differentiated cells. Many studies have achieved direct conversion into various cell types in recent years, and this strategy is considered to be a promising approach for inducing functional cells. Here, we review work on direct reprogramming, from the early pioneering studies to the most recent, including the discovery of novel reprogramming factors, molecular mechanisms, and strategies. We also discuss the applications of direct reprogramming and the perspectives and challenges of this novel technology.
URI
https://synapse.koreamed.org/DOIx.php?id=10.7599/hmr.2015.35.4.215http://hdl.handle.net/20.500.11754/29514
ISSN
1738-429X; 2234-4446
DOI
10.7599/hmr.2015.35.4.215
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
The current status of directed differentiation technology.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE