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dc.contributor.author은창수-
dc.date.accessioned2017-09-22T07:26:40Z-
dc.date.available2017-09-22T07:26:40Z-
dc.date.issued2015-12-
dc.identifier.citationGASTROINTESTINAL ENDOSCOPY, v. 82, NO 6, Page. 1087-1093en_US
dc.identifier.issn0016-5107-
dc.identifier.issn1097-6779-
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0016510715024359?via%3Dihub-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/29323-
dc.description.abstractBackground and Aims: Although the malignant progression of serrated polyps has been clearly documented, the malignant potential of the traditional serrated adenoma (TSA) subtype has not been established. We compared the prevalence of metachronous polyps in surveillance colonoscopies between patients with TSA and those with conventional adenomas (CAs). Methods: Four hundred twenty patients were diagnosed with TSAs by current diagnostic criteria at 10 tertiary care university hospitals in Korea from January 2003 to December 2005; 186 patients who received surveillance colonoscopy after removal of initial polyps were enrolled. During the same time period, 372 age- and sex-matched patients diagnosed with CAs were used as a control group. Results: TSA patients had a significantly higher recurrence rate of colorectal polyps compared with CA patients (66.1% vs 43.5%, respectively). TSA patients had a greater number (3 vs 2) and larger size (8.6 +/- 5.7 vs 6.3 +/- 5.2 mm) of recurrent polyps compared with CA patients. TSA patients also had a higher rate of CA (54.8% vs 37.9%), serrated adenoma (14.0% vs. 0.8%), and hyperplastic polyp (33.3% vs. 13.7%) recurrence compared with CA patients. TSA patients had significantly greater odds of having a recurrent high-risk polyp than CA patients (odds ratio, 2.37; 95% confidence interval, 1.55-3.63). Conclusions: In comparison with patients with CAs, patients with TSAs have a higher metachronous occurrence rate of all polyp subtypes including CAs, serrated adenomas, and hyperplastic polyps. Moreover, the presence of TSAs is an independent predictor of a high-risk polyp occurrence.en_US
dc.description.sponsorshipAll authors disclosed no financial relationships relevant to this publication. Research support for this study was provided by the Intestinal Tumor Research Group of the Korean Association for the Study of Intestinal Diseases.en_US
dc.language.isoenen_US
dc.publisherMOSBY-ELSEVIERen_US
dc.subjectSOCIETY-TASK-FORCEen_US
dc.subjectAMERICAN-CANCER-SOCIETYen_US
dc.subjectON-COLORECTAL-CANCERen_US
dc.subjectCOLONOSCOPY SURVEILLANCEen_US
dc.subjectHYPERPLASTIC POLYPSen_US
dc.subjectCONSENSUS UPDATEen_US
dc.subjectNEOPLASIA PATHWAYen_US
dc.subjectKRAS MUTATIONSen_US
dc.subjectCOLON POLYPSen_US
dc.subjectGUIDELINESen_US
dc.titleHigh-risk metachronous polyps are more frequent in patients with traditional serrated adenomas than in patients with conventional adenomas: a multicenter prospective studyen_US
dc.typeArticleen_US
dc.relation.no6-
dc.relation.volume82-
dc.identifier.doi10.1016/j.gie.2015.05.016-
dc.relation.page1087-1093-
dc.relation.journalGASTROINTESTINAL ENDOSCOPY-
dc.contributor.googleauthorYoon, Jin Young-
dc.contributor.googleauthorKim, Hyung Tae-
dc.contributor.googleauthorHong, Sung Pil-
dc.contributor.googleauthorKim, Hyun Gun-
dc.contributor.googleauthorKim, Jin-Oh-
dc.contributor.googleauthorYang, Dong-Hoon-
dc.contributor.googleauthorPark, Dong Il-
dc.contributor.googleauthorPark, Seun Ja-
dc.contributor.googleauthorKim, Hyun-Soo-
dc.contributor.googleauthorEun, Chang Soo-
dc.relation.code2015000905-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidcseun-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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