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dc.contributor.author신정훈-
dc.date.accessioned2017-09-08T01:41:08Z-
dc.date.available2017-09-08T01:41:08Z-
dc.date.issued2015-11-
dc.identifier.citationJOURNAL OF WOMENS HEALTH, v. 24, NO 12, Page. 1021-1029en_US
dc.identifier.issn1540-9996-
dc.identifier.issn1931-843X-
dc.identifier.urihttp://online.liebertpub.com/doi/10.1089/jwh.2015.5358-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/28975-
dc.description.abstractBackground: Inconsistent results regarding the association between low vitamin D level and hypertension (HTN) have led to uncertainty in clinical practice as to the use of vitamin D cutoff value. The aims of this study were to investigate the association between vitamin D deficiency and HTN in postmenopausal women and to determine the clinically significant cutoff value for vitamin D deficiency. Methods: We analyzed data from the Korean National Health and Nutrition Examination Survey 5 database (4107 postmenopausal women, aged 50-79 years). The cutoff value for vitamin D deficiency was based on the changes in parathyroid hormone (PTH) level according to serum 25(OH)D value. Results: PTH levels were significantly higher in groups with serum 25(OH)D ˂15ng/mL (p˂0.001). When a serum 25(OH)D value of 15ng/mL was used as a cutoff value, 35.2% of the subjects were found to be vitamin D deficient. Although the association between 25(OH)D level ˂15ng/mL and systolic blood pressure did not remain significant after adjusting for season (p=0.30), multiple logistic regression analysis revealed that 25(OH)D level ˂15ng/mL was an independent risk factor for HTN (adjusted odds ratio [OR] 1.285, 95% confidence interval [CI] 1.024-1.614, p=0.031). Conclusions: Using serum PTH level, we defined vitamin D deficiency as 25(OH)D ˂15ng/mL in postmenopausal women. Vitamin D deficiency [25(OH)D ˂15ng/mL] was a significant risk factor for HTN in postmenopausal women.en_US
dc.description.sponsorshipWe thank the Korea Centers for Disease Control and Prevention, which collected the data for the KNHANES. We also thank all of the participants for their generous cooperation. This work was supported by the research fund of Hanyang University (HY-2015).en_US
dc.language.isoenen_US
dc.publisherMARY ANN LIEBERTen_US
dc.subjectNUTRITION EXAMINATION SURVEYen_US
dc.subjectPARATHYROID-HORMONE LEVELSen_US
dc.subjectGENOME-WIDE ASSOCIATIONen_US
dc.subjectBODY-FAT DISTRIBUTIONen_US
dc.subjectBLOOD-PRESSUREen_US
dc.subjectNATIONAL-HEALTHen_US
dc.subjectD SUPPLEMENTATIONen_US
dc.subjectSERUM 25-HYDROXYVITAMIN-Den_US
dc.subject1,25-DIHYDROXYVITAMIN D-3en_US
dc.subjectHYPOVITAMINOSIS Den_US
dc.titleDefining Vitamin D Deficiency and Its Relationship to Hypertension in Postmenopausal Korean Womenen_US
dc.typeArticleen_US
dc.relation.no12-
dc.relation.volume24-
dc.identifier.doi10.1089/jwh.2015.5358-
dc.relation.page1021-1029-
dc.relation.journalJOURNAL OF WOMENS HEALTH-
dc.contributor.googleauthorShin, Jeong-Hun-
dc.contributor.googleauthorLee, Hyung Tak-
dc.contributor.googleauthorLim, Young-Hyo-
dc.contributor.googleauthorPark, Hwan-Cheol-
dc.contributor.googleauthorShin, Jinho-
dc.contributor.googleauthorKim, Kyung-Soo-
dc.contributor.googleauthorPark, Jin-Kyu-
dc.relation.code2015000066-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidhyapex-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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