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dc.contributor.author손주현-
dc.date.accessioned2017-08-22T05:30:49Z-
dc.date.available2017-08-22T05:30:49Z-
dc.date.issued2015-11-
dc.identifier.citationLIVER INTERNATIONAL, v. 35, NO 11, Page. 2416-2424en_US
dc.identifier.issn1478-3223-
dc.identifier.issn1478-3231-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1111/liv.12846/abstract;jsessionid=DF79E128BA69EC3AD5C10DD376DC14C0.f03t02-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/28695-
dc.description.abstractBackground & AimsTo assess the correlation between liver stiffness measurement (LSM) by real-time shear wave elastography (SWE) and hepatic venous pressure gradient (HVPG) and to investigate the diagnostic performance of SWE for predicting clinically significant and severe portal hypertension (CSPH and SPH). MethodsClinical data of 115 cirrhotic patients with haemodynamic measurement were consecutively collected. Liver stiffness (LS) was measured using SWE by repeated performance five times per patient, and the median value and interquartile range of the parameters on the same day of HVPG measurement was calculated. CSPH and SPH were defined as a HVPG 10mmHg and 12mmHg respectively. ResultsA total of 92 patients (male, 63; mean age, 5311.9years) were eligible for analysis. CSPH and SPH were detected in 77 patients (83.7%) and 66 patients (71.5%) respectively. HVPG were significantly correlated with LSM in the overall, CSPH, and SPH patients (r=0.646, 0.574 and 0.424 respectively; all P<0.001). With ascites, the correlation coefficient did not decrease (r=0.587). The AUROCs of LSM was 0.819 (95% CI, 0.725-0.892) for CSPH and 0.867 (95% CI, 0.780-0.928) for SPH. The cut-off values for determining CSPH and SPH were 15.2kPa (Sensitivity, 85.7%; Specificity, 80.0%) and 21.6 kPa (Sensitivity, 83.3%; Specificity, 80.8%) respectively. ConclusionIn cirrhotic patients, LSM by SWE is highly correlated with HVPG value regardless of ascites. SWE is a new reliable non-invasive diagnostic tool to predict CSPH and SPH, even in cirrhotic patients with ascites.en_US
dc.description.sponsorshipThis study was partly supported by the research fund of the Hanyang University (HY-2010-G).en_US
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.subjectcirrhosisen_US
dc.subjectelastographyen_US
dc.subjectshear waveen_US
dc.subjecthepatic venous pressure gradienten_US
dc.subjectliver stiffnessen_US
dc.subjectportal hypertensionen_US
dc.titleEvaluation of portal hypertension by real-time shear wave elastography in cirrhotic patientsen_US
dc.typeArticleen_US
dc.relation.no11-
dc.relation.volume35-
dc.identifier.doi10.1111/liv.12846-
dc.relation.page2416-2424-
dc.relation.journalLIVER INTERNATIONAL-
dc.contributor.googleauthorKim, Tae Yeob-
dc.contributor.googleauthorJeong, Woo Kyoung-
dc.contributor.googleauthorSohn, Joo Hyun-
dc.contributor.googleauthorKim, Jinoo-
dc.contributor.googleauthorKim, Min Yeong-
dc.contributor.googleauthorKim, Yongsoo-
dc.relation.code2015000913-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidsonjh-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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