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Biocompatible responsive polypyrrole/GO nanocomposite coatings for biomedical applications

Title
Biocompatible responsive polypyrrole/GO nanocomposite coatings for biomedical applications
Author
김계성
Keywords
316L SS; ELECTROCHEMICAL ASPECTS; OXIDE NANOCOMPOSITES; ORTHOPEDIC IMPLANTS; GRAPHENE; NANOPARTICLES; SURFACE
Issue Date
2015-11
Publisher
ROYAL SOC CHEMISTRY
Citation
RSC ADVANCES, v. 5, NO 121, Page. 99866-99874
Abstract
Hybrid implant coating materials composed of at least two constituents of different chemistry, functionality, and biocompatibility have attracted attention in a wide range of biomedical applications. One-step electrosynthesis of polypyrrole (PPy)/graphene oxide (GO) nanocomposites on 316L SS implants was achieved by electropolymerization of pyrrole using different amounts of GO. Possible interaction between the PPy chain and GO nanosheet was examined by structural characterizations including UV-visible, X-ray diffraction, Raman, and X-ray photoelectron spectroscopy analyses. Morphological study by scanning electron microscopy and transmission electron microscopy confirmed dispersion of the GO nanosheets within the PPy matrix. Further, in vitro cell culture studies were carried out using MG-63 human osteoblast cells to estimate the biocompatibility of PPy/GO coatings. Noticeable improvements in surface protective and biocompatibility performance suggest possible application as a bioactive coating material on 316L SS implants for biomedical fields.
URI
http://pubs.rsc.org/en/Content/ArticleLanding/2015/RA/C5RA14464G#!divAbstracthttp://hdl.handle.net/20.500.11754/28583
ISSN
2046-2069
DOI
10.1039/c5ra14464g
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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