138 0

Nonlinear analysis of fetal heart rate dynamics in fetuses compromised by asymptomatic partial placental abruption

Title
Nonlinear analysis of fetal heart rate dynamics in fetuses compromised by asymptomatic partial placental abruption
Author
호정규
Keywords
Approximate entropy; Correlation dimension; Fetal heart rate; Nonlinear dynamic indices; Partial placental abruption; Sample entropy; Short-term and long-term scaling exponents
Issue Date
2015-10
Publisher
W B SAUNDERS CO LTD
Citation
PLACENTA, v. 36, NO 12, Page. 1474-1479
Abstract
Introduction: We analyzed fetal heart rate (FHR) parameters, dynamics, and outcomes in pregnancies with asymptomatic partial placental abruption (PPA) compared with those in normal pregnancies. Methods: We examined nonstress test (NST) data acquired from 2003 to 2012 at our institution. Normal pregnancies (N = 170) and PPA cases (N = 17) were matched for gestational age, fetal sex, and mean FHR. NSTs were performed at 33-42 weeks of gestation. FHR parameters obtained from the NST and perinatal outcomes were analyzed using linear methods. Nonlinear indices, including approximate entropy (ApEn), sample entropy (SampEn), short-term and long-term scaling exponents (alpha(1) and alpha(2)), and correlation dimension (CD), were used to interpret FHR dynamics and system complexity. The area under a receiver operating characteristic curve (AUC) was used to evaluate the nonlinear indices. Results: There were no significant differences in general characteristics and FHR parameters between the PPA and control groups. However, gestational age at delivery, birth weight, 5-min Apgar scores, ApEn, SampEn, and CD were significantly lower in the PPA group than in the control group (P < 0.05). The long-term scaling exponent (alpha(2)) and crossover index (alpha(2)/alpha(1)) of the PPA fetuses were significantly higher than those of the controls (P < 0.01). A multiple regression model showed better performance in predicting PPA (AUC, 0.92; sensitivity 82.35%; specificity, 94.12%). Discussion: Nonlinear dynamic indices of FHR in asymptomatic PPA were qualitatively different from those in normal pregnancies, whereas the conventional FHR parameters were not significantly different. (C) 2015 Elsevier Ltd. All rights reserved.
URI
http://www.sciencedirect.com/science/article/pii/S014340041530062X?via%3Dihubhttp://hdl.handle.net/20.500.11754/28283
ISSN
0143-4004; 1532-3102
DOI
10.1016/j.placenta.2015.10.002
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE