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dc.contributor.authorKlaus Heese-
dc.date.accessioned2017-07-31T07:03:40Z-
dc.date.available2017-07-31T07:03:40Z-
dc.date.issued2015-10-
dc.identifier.citationEVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, Page. 1-17en_US
dc.identifier.issn1741-427X-
dc.identifier.issn1741-4288-
dc.identifier.urihttps://www.hindawi.com/journals/ecam/2015/393510/-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/28144-
dc.description.abstractIn recent years, there has been an increasing worldwide interest in traditional Chinese medicine (TCM). This increasing demand for TCM needs to be accompanied by a deeper understanding of the mechanisms of action of TCM-based therapy. However, TCM is often described as a concept of Chinese philosophy, which is incomprehensible for Western medical society, thereby creating a gap between TCM and Western medicine (WM). In order to meet this challenge, TCM research has applied proteomics technologies for exploring the mechanisms of action of TCM treatment. Proteomics enables TCM researchers to oversee various pathways that are affected by treatment, as well as the dynamics of their interactions with one another. This review discusses the utility of comparative proteomics to better understand how TCM treatment may be used as a complementary therapy for Alzheimer's disease (AD). Additionally, we review the data from comparative AD-related TCM proteomics studies and establish the relevance of the data with available AD hypotheses, most notably regarding the ubiquitin proteasome system (UPS).en_US
dc.description.sponsorshipThis work was supported by the research fund of Hanyang University.en_US
dc.language.isoenen_US
dc.publisherHINDAWI PUBLISHING CORPORATIONen_US
dc.subjectAMYLOID-BETA-PROTEINen_US
dc.subjectINTRINSICALLY DISORDERED PROTEINSen_US
dc.subjectACANTHOPANAX-SENTICOSUS HARMSen_US
dc.subjectUBIQUITIN-PROTEASOME SYSTEMen_US
dc.subjectTRANSIENT CEREBRAL-ISCHEMIAen_US
dc.subjectRADICAL OXIDATIVE STRESSen_US
dc.subjectBILOBA EXTRACT EGB-761en_US
dc.subjectMUTANT ALPHA-SYNUCLEINen_US
dc.subjectTERMINAL HYDROLASE L1en_US
dc.subjectGINKGO-BILOBAen_US
dc.titleProteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer's Diseaseen_US
dc.typeArticleen_US
dc.identifier.doi10.1155/2015/393510-
dc.relation.page1-17-
dc.relation.journalEVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE-
dc.contributor.googleauthorSulistio, Yanuar Alan-
dc.contributor.googleauthorHeese, Klaus-
dc.relation.code2015012377-
dc.sector.campusS-
dc.sector.daehakGraduate School of Biomedical Science & Engineering[S]-
dc.identifier.pidklaus-
dc.identifier.researcherIDH-3128-2013-
dc.identifier.orcidhttp://orcid.org/0000-0002-0027-6993-


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