Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경래 | - |
dc.date.accessioned | 2017-04-24T05:58:33Z | - |
dc.date.available | 2017-04-24T05:58:33Z | - |
dc.date.issued | 2015-08 | - |
dc.identifier.citation | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, v. 124, NO 8, Page. 663-670 | en_US |
dc.identifier.issn | 0003-4894 | - |
dc.identifier.issn | 1943-572X | - |
dc.identifier.uri | http://journals.sagepub.com/doi/abs/10.1177/0003489415576181 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/26897 | - |
dc.description.abstract | Objectives: To investigate the impact of olfactory dysfunction on quality of life (QOL) and psychological status in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: A retrospective observational study was conducted from January 2011 to May 2012 with 130 patients with septal deviation (SD) (n = 59) and CRSwNP (n = 71). All patients underwent computed tomography (CT), allergy tests, and sniffin' stick olfactory test. Anosmia was defined by Threshold-Discrimination-Identification (TDI) scores less than 16. QOL and psychological symptoms were assessed with the Sinonasal Outcome Test-20 (SNOT-20) and Symptom Checklist-90-Revised (SCL-90-R). Results: Odor discrimination and identification scores were significantly lower in CRSwNP than in SD (P = .008 and P = .005, respectively). In CRSwNP, identification score decreased with higher CT score (r = -0.29, P = .014). CRSwNP with anosmia showed a decreased QOL (P = .044), and SNOT-20 negatively correlated with TDI in severe CRSwNP (CT score 15, r = -0.714, P = .001). Anosmia patients had higher anxiety and phobia scores of SCL-90-R in both SD and CRSwNP. However, depression score increased only in CRSwNP with anosmia (P = .025). Conclusion: Olfactory dysfunction may have significant effects on QOL and psychological health. CRSwNP with anosmia is a distinct phenotype having mixed type of olfactory loss that might have a detrimental effect on depression. | en_US |
dc.description.sponsorship | The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported by the Basic Science Research Program of the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (NRF-2013R1A1A2007651). Role of the Sponsor: Research Foundation of Korea had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication | en_US |
dc.language.iso | en | en_US |
dc.publisher | SAGE PUBLICATIONS INC | en_US |
dc.subject | nasal obstruction | en_US |
dc.subject | nasal polyposis | en_US |
dc.subject | olfaction | en_US |
dc.subject | otolaryngology | en_US |
dc.subject | rhinology | en_US |
dc.subject | sinusitis | en_US |
dc.title | Altered Quality of Life and Psychological Health (SCL-90-R) in Patients With Chronic Rhinosinusitis With Nasal Polyps | en_US |
dc.type | Article | en_US |
dc.relation.no | 8 | - |
dc.relation.volume | 124 | - |
dc.identifier.doi | 10.1177/0003489415576181 | - |
dc.relation.page | 663-670 | - |
dc.relation.journal | ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | - |
dc.contributor.googleauthor | Chung, Jae Ho | - |
dc.contributor.googleauthor | Lee, Yun Jae | - |
dc.contributor.googleauthor | Kang, Tae Wook | - |
dc.contributor.googleauthor | Kim, Kyung Rae | - |
dc.contributor.googleauthor | Jang, Dong Pyo | - |
dc.contributor.googleauthor | Kim, In Young | - |
dc.contributor.googleauthor | Cho, Seok Hyun | - |
dc.relation.code | 2015000092 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | krkim | - |
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