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Successful treatment with ultrasound-guided aspiration of intractable methicillin-resistant Staphylococcus aureus brain abscess in an extremely low birth weight infant

Title
Successful treatment with ultrasound-guided aspiration of intractable methicillin-resistant Staphylococcus aureus brain abscess in an extremely low birth weight infant
Author
오성희
Keywords
Methicillin-resistant Staphylococcus aureus; Brain abscess; Development
Issue Date
2015-07
Publisher
Karger
Citation
Pediatric Neurosurgery, v. 50, NO 4, Page. 210-215
Abstract
Brain abscesses are an uncommon and devastating complication of bacteremia in extremely low birth weight infants (˂1 kg). We report a 25-week preterm neonate who developed a brain abscess 4 weeks following methicillin-resistant Staphyloccocus aureus (MRSA) sepsis. A huge brain abscess was seen with routine brain sonography on day 19 of life. Despite intravenous vancomycin treatment, the brain abscess increased in size and was associated with increased intracranial pressure on day 49 of life. The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures. Diagnosis of abscess was confirmed by bedside ultrasound-guided aspiration, and MRSA was isolated from the pus culture. The MRSA brain abscess refractory to vancomycin was successfully treated by surgical ultrasound-guided percutaneous needle aspiration of brain abscess and prolonged courses of antibiotic administration. At the time of this report, the infant was 9 months old (corrected age was 6 months) and had normal neurodevelopment for her corrected age on the Bayley Infant Neurodevelopmental Screener.
URI
http://www.karger.com/article/FullText/381749http://hdl.handle.net/20.500.11754/26436
ISSN
1016-2291; 1423-0305
DOI
10.1159/000381749
Appears in Collections:
COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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