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dc.contributor.author채필석-
dc.date.accessioned2017-03-14T07:10:17Z-
dc.date.available2017-03-14T07:10:17Z-
dc.date.issued2015-07-
dc.identifier.citationANALYTICAL METHODS, v. 7, NO 14, Page. 5808-5813en_US
dc.identifier.issn1759-9660-
dc.identifier.issn1759-9679-
dc.identifier.urihttp://pubs.rsc.org/en/Content/ArticleLanding/2015/AY/C4AY03091E#!divAbstract-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/26104-
dc.description.abstractMembrane protein manipulation is known to be an extremely challenging task, mainly because of incompatibility between the hydrophobic surface area of proteins and the hydrophilic character of an aqueous medium. To avoid protein degradation resulting from this incompatibility, detergents are used as essential tools in the study of membrane proteins. However, traditional detergents have a limited ability to stabilize the native conformation of membrane proteins. This study introduces a novel tripod amphiphile that can be prepared efficiently from a commercially available compound. The new agent proved effective for the long-term stability of a multi-subunit superassembly, a membrane protein sensitive to denaturation.en_US
dc.description.sponsorshipThis work was supported by the research fund of Hanyang University (HY-2013-N).en_US
dc.language.isoenen_US
dc.publisherROYAL SOC CHEMISTRYen_US
dc.subjectMUSCARINIC ACETYLCHOLINE-RECEPTORen_US
dc.subjectFACIAL AMPHIPHILESen_US
dc.subjectAQUEOUS-SOLUTIONSen_US
dc.subjectCRYSTAL-STRUCTUREen_US
dc.subjectMNG AMPHIPHILESen_US
dc.subjectGNG AMPHIPHILESen_US
dc.subjectSTABILIZATIONen_US
dc.subjectSOLUBILIZATIONen_US
dc.subjectDETERGENTen_US
dc.subjectCRYSTALLIZATIONen_US
dc.titleAccessible glyco-tripod amphiphiles for membrane protein analysisen_US
dc.typeArticleen_US
dc.relation.no14-
dc.relation.volume7-
dc.identifier.doi10.1039/c4ay03091e-
dc.relation.page5808-5813-
dc.relation.journalANALYTICAL METHODS-
dc.contributor.googleauthorDas, Manabendra-
dc.contributor.googleauthorBae, Hyoung Eun-
dc.contributor.googleauthorLee, Ho Jin-
dc.contributor.googleauthorGo, Juyeon-
dc.contributor.googleauthorChae, Pil Seok-
dc.relation.code2015006710-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidpchae-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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