Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진웅 | - |
dc.date.accessioned | 2017-03-03T02:38:25Z | - |
dc.date.available | 2017-03-03T02:38:25Z | - |
dc.date.issued | 2015-06 | - |
dc.identifier.citation | RSC ADVANCES, v. 5, NO 57, Page. 46276-46281 | en_US |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | http://pubs.rsc.org/en/content/articlehtml/2015/ra/c5ra03872c | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/25815 | - |
dc.description.abstract | This study introduces a robust approach for the fabrication of extremely stable oil-in-water nanoemulsions in which the interface is stabilized by assembly of amphiphilic poly(ethylene oxide)-block-poly(3-caprolactone) (PEO-b-PCL) copolymers. Phase inversion emulsification, induced by variation of the water volume fraction, facilitated effective assembly of the block copolymers at the oil-water interface. Subsequent application of simple probe-type sonication reduced the droplet size of the precursor emulsions to approximately 200 nm. The prepared nanoemulsions were surprisingly stable against drop coalescence and aggregation, as confirmed by analysis of changes in the droplet size after repeated freeze-thaw cycling and by monitoring the creaming kinetics under conditions of high ionic strength and density mismatch. The results highlight that good structural assembly of the PEO-b-PCL block copolymers at the oil-water interface generated a mechanically flexible but tough polymer film, thereby remarkably improving the emulsion stability. | en_US |
dc.description.sponsorship | This work was supported by a grant of the Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (Grant no.: A103017). This research was also supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2012R1A1A2039). | en_US |
dc.language.iso | en | en_US |
dc.publisher | ROYAL SOC CHEMISTRY | en_US |
dc.subject | PEO TRIBLOCK COPOLYMERS | en_US |
dc.subject | PHASE INVERSION TEMPERATURE | en_US |
dc.subject | NANO-EMULSIONS | en_US |
dc.subject | BLOCK-COPOLYMERS | en_US |
dc.subject | TOPICAL DELIVERY | en_US |
dc.subject | EMULSIFICATION | en_US |
dc.subject | POINT | en_US |
dc.subject | MICROEMULSIONS | en_US |
dc.subject | NANOEMULSIONS | en_US |
dc.subject | TRANSITION | en_US |
dc.title | Fabrication and stabilization of nanoscale emulsions by formation of a thin polymer membrane at the oil-water interface | en_US |
dc.type | Article | en_US |
dc.relation.no | 57 | - |
dc.relation.volume | 5 | - |
dc.identifier.doi | 10.1039/c5ra03872c | - |
dc.relation.page | 46276-46281 | - |
dc.relation.journal | RSC ADVANCES | - |
dc.contributor.googleauthor | Shin, Kyounghee | - |
dc.contributor.googleauthor | Kim, Jeong Won | - |
dc.contributor.googleauthor | Park, Hanhee | - |
dc.contributor.googleauthor | Choi, Hong Sung | - |
dc.contributor.googleauthor | Chae, Pil Seok | - |
dc.contributor.googleauthor | Nam, Yoon Sung | - |
dc.contributor.googleauthor | Kim, Jin Woong | - |
dc.relation.code | 2015011569 | - |
dc.sector.campus | S | - |
dc.sector.daehak | GRADUATE SCHOOL[S] | - |
dc.sector.department | DEPARTMENT OF BIONANOTECHNOLOGY | - |
dc.identifier.pid | kjwoong | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.