Differences in early speech patterns between Parkinson variant of multiple system atrophy and Parkinson's disease
- Title
- Differences in early speech patterns between Parkinson variant of multiple system atrophy and Parkinson's disease
- Author
- 김희태
- Keywords
- Multiple system atrophy; Parkinson's disease; Speech; Acoustic analysis; Perceptual analysis
- Issue Date
- 2015-05
- Publisher
- ACADEMIC PRESS INC ELSEVIER SCIENCE
- Citation
- BRAIN AND LANGUAGE, v. 147, Page. 14-20
- Abstract
- In Parkinson variant of multiple system atrophy (MSA-P), patterns of early speech impairment and their distinguishing features from Parkinson's.disease (PD) require further exploration. Here, we compared speech data among patients with early-stage MSA-P, PD, and healthy subjects using quantitative acoustic and perceptual analyses. Variables were analyzed for men and women in view of gender-specific features of speech. Acoustic analysis revealed that male patients with MSA-P exhibited more profound speech abnormalities than those with PD, regarding increased voice pitch, prolonged pause time, and reduced speech rate. This might be due to widespread pathology of MSA-P in nigrostriatal or extra-striatal structures related to speech production. Although several perceptual measures were mildly impaired in MSA-P and PD patients, none of these parameters showed a significant difference between patient groups. Detailed speech analysis using acoustic measures may help distinguish between MSA-P and PD early in the disease process. (C) 2015 Elsevier Inc. All rights reserved.
- URI
- http://www.sciencedirect.com/science/article/pii/S0093934X15000930http://hdl.handle.net/20.500.11754/24638
- ISSN
- 0093-934X; 1090-2155
- DOI
- 10.1016/j.bandl.2015.04.007
- Appears in Collections:
- COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML