Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김민규 | - |
dc.date.accessioned | 2016-09-27T00:56:38Z | - |
dc.date.available | 2016-09-27T00:56:38Z | - |
dc.date.issued | 2015-03 | - |
dc.identifier.citation | WORLD JOURNAL OF SURGERY, v. 39, NO 3, Page. 732-739 | en_US |
dc.identifier.issn | 0364-2313 | - |
dc.identifier.issn | 1432-2323 | - |
dc.identifier.uri | http://search.proquest.com/docview/1652638221?accountid=11283 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11754/23458 | - |
dc.description.abstract | Background The aim of this study was to investigate the prognostic value of lymphovascular invasion (LVI) in gastric cancer patients without lymph node metastasis. Methods A total of 699 patients with primary tumor pT1-3/pN0-1 gastric adenocarcinoma who underwent curative resection from 2001 to 2010 were categorized into 3 groups: One-hundred and eleven patients with pN0/LVI(+), 475 with pN0/LVI(-), and 103 with pN1. Results The tumors in patients with N0/LVI(+) had more aggressive clinicopathologic features than those in patients with N0/LVI(-). However, there was no significant difference in patient characteristics between patients with pN0/LVI(+) and those with pN1, except for histologic grade. There were no significant differences in the overall survival rate in patients with pN0/LVI(+) compared to those with pN0/LVI(-) or the pN1 stage. However, the recurrence-free survival rate of the pN0/LVI(+) group was lower than that of the pN0/LVI(-) group (p ˂ 0.001), while no significant difference was observed between the pN0/LVI(+) and the N1 groups (p = 0.216). In multi-variate analysis, LVI was identified as a poor prognostic factor related to recurrence-free survival in node-negative gastric cancer patients. pT3 stage and less than D2 lymphadenectomy were poor prognostic factors affecting recurrence-free survival, and less than D2 lymphadenectomy was an independent poor prognostic factor for overall survival in pN0/LVI(+) patients. Conclusions LVI could be an indicator of biological aggressiveness and may be a reliable prognostic factor for node-negative gastric cancer. LVI should be considered in postoperative management of gastric cancer. | en_US |
dc.language.iso | en | en_US |
dc.publisher | SPRINGER | en_US |
dc.subject | VESSEL INVASION | en_US |
dc.subject | METASTASIS | en_US |
dc.subject | IMPACT | en_US |
dc.subject | BLOOD | en_US |
dc.title | Prognostic Significance of Lymphovascular Invasion in Node-Negative Gastric Cancer | en_US |
dc.type | Article | en_US |
dc.relation.no | 3 | - |
dc.relation.volume | 39 | - |
dc.identifier.doi | 10.1007/s00268-014-2846-y | - |
dc.relation.page | 732-739 | - |
dc.relation.journal | WORLD JOURNAL OF SURGERY | - |
dc.contributor.googleauthor | Lee, Ju-Hee | - |
dc.contributor.googleauthor | Kim, Min Gyu | - |
dc.contributor.googleauthor | Jung, Min-Sung | - |
dc.contributor.googleauthor | Kwon, Sung Joon | - |
dc.relation.code | 2015002021 | - |
dc.sector.campus | S | - |
dc.sector.daehak | COLLEGE OF MEDICINE[S] | - |
dc.sector.department | DEPARTMENT OF MEDICINE | - |
dc.identifier.pid | md9650 | - |
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