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dc.contributor.author장동표-
dc.date.accessioned2016-08-31T01:15:55Z-
dc.date.available2016-08-31T01:15:55Z-
dc.date.issued2015-03-
dc.identifier.citationAnnals of Otology, Rhinology and Laryngology, Page. 663-670en_US
dc.identifier.issn0003-4894-
dc.identifier.issn1943-572X-
dc.identifier.urihttp://aor.sagepub.com/content/124/8/663.short-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/22906-
dc.description.abstractObjectives: To investigate the impact of olfactory dysfunction on quality of life (QOL) and psychological status in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: A retrospective observational study was conducted from January 2011 to May 2012 with 130 patients with septal deviation (SD) (n = 59) and CRSwNP (n = 71). All patients underwent computed tomography (CT), allergy tests, and sniffin' stick olfactory test. Anosmia was defined by Threshold-Discrimination-Identification (TDI) scores less than 16. QOL and psychological symptoms were assessed with the Sinonasal Outcome Test-20 (SNOT-20) and Symptom Checklist-90-Revised (SCL-90-R). Results: Odor discrimination and identification scores were significantly lower in CRSwNP than in SD (P = .008 and P = .005, respectively). In CRSwNP, identification score decreased with higher CT score (r = -0.29, P = .014). CRSwNP with anosmia showed a decreased QOL (P = .044), and SNOT-20 negatively correlated with TDI in severe CRSwNP (CT score 15, r = -0.714, P = .001). Anosmia patients had higher anxiety and phobia scores of SCL-90-R in both SD and CRSwNP. However, depression score increased only in CRSwNP with anosmia (P = .025). Conclusion: Olfactory dysfunction may have significant effects on QOL and psychological health. CRSwNP with anosmia is a distinct phenotype having mixed type of olfactory loss that might have a detrimental effect on depression.en_US
dc.description.sponsorshipBasic Science Research Program of the National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technologyen_US
dc.language.isoenen_US
dc.publisherAnnals Publishing Co.en_US
dc.subjectnasal obstructionen_US
dc.subjectnasal polyposisen_US
dc.subjectolfactionen_US
dc.subjectotolaryngologyen_US
dc.subjectrhinologyen_US
dc.subjectsinusitisen_US
dc.titleAltered Quality of Life and Psychological Health (SCL-90-R) in Patients With Chronic Rhinosinusitis With Nasal Polypsen_US
dc.typeArticleen_US
dc.identifier.doi10.1177/0003489415576181-
dc.relation.page1-8-
dc.relation.journalAnnals of Otology, Rhinology and Laryngology-
dc.contributor.googleauthorChung, Jae Ho-
dc.contributor.googleauthorLee, Yun Jae-
dc.contributor.googleauthorKang, Tae Wook-
dc.contributor.googleauthorKim, Kyung Rae-
dc.contributor.googleauthorJang, Dong Pyo-
dc.contributor.googleauthorKim, In Young-
dc.contributor.googleauthorCho, Seok Hyun-
dc.relation.code2015018671-
dc.sector.campusS-
dc.sector.daehakGraduate School of Biomedical Science & Engineering[S]-
dc.identifier.piddongpjang-
Appears in Collections:
GRADUATE SCHOOL OF BIOMEDICAL SCIENCE AND ENGINEERING[S](의생명공학전문대학원) > ETC
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