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dc.contributor.author구혜령-
dc.date.accessioned2016-08-11T01:41:14Z-
dc.date.available2016-08-11T01:41:14Z-
dc.date.issued2015-02-
dc.identifier.citationAMERICAN JOURNAL OF ROENTGENOLOGY, v. 204, NO 2, Page. 396-401en_US
dc.identifier.issn0361-803X-
dc.identifier.issn1546-3141-
dc.identifier.urihttp://www.ajronline.org/doi/abs/10.2214/AJR.14.12871-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/22508-
dc.description.abstractOBJECTIVE. The purpose of this study was to evaluate the diagnostic performance of gray-scale ultrasound and a new method of thyroid ultrasound elastography using carotid artery pulsation in the differential diagnosis of sonographically indeterminate thyroid nodules. MATERIALS AND METHODS. A total of 102 thyroid nodules with indeterminate gray-scale ultrasound features from 102 patients (20 males and 82 females; age range, 16-74 years; mean age, 51 years) were included. The gray-scale ultrasound images of each nodule were reviewed and assigned a score from 1 (low) to 5 (high) according to the possibility of malignancy. Ultrasound elastography was performed using carotid pulsation as the compression source. The elasticity contrast index (ECI), which quantifies local strain contrast within a nodule, was automatically calculated. The radiologist reassessed the scores after concurrently reviewing gray-scale ultrasound and elastography. ROC curve analysis was used to evaluate the diagnostic performances of each dataset and to compare the AUC (A(z)) values of gray-scale ultrasound score alone, ECI alone, and a combined assessment. RESULTS. Significantly more malignant thyroid nodules were hypoechoic than benign nodules (p = 0.014). The ECI was significantly higher in malignant nodules than in benign thyroid nodules. The A(z) values of each dataset were 0.755 (95% CI, 0.660-0.835) for gray-scale ultrasound score, 0.835 (0.748-0.901) for ECI, and 0.853 (0.769-0.915) for a combined assessment. The A(z) value for a combined assessment of the gray-scale ultrasound score and the ECI was significantly higher than that for the gray-scale ultrasound score alone (p = 0.022). CONCLUSION. Combined assessment with gray-scale ultrasound and elastography using carotid artery pulsation is helpful for characterizing sonographically indeterminate thyroid nodules as benign or malignant.en_US
dc.description.sponsorshipBasic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technologyen_US
dc.language.isoenen_US
dc.publisherAMER ROENTGEN RAY SOCen_US
dc.subjectcarotid artery pulsationen_US
dc.subjectelastographyen_US
dc.subjectthyroid noduleen_US
dc.subjectthyroid ultrasounden_US
dc.titleUltrasound Elastography Using Carotid Artery Pulsation in the Differential Diagnosis of Sonographically Indeterminate Thyroid Nodulesen_US
dc.typeArticleen_US
dc.relation.no2-
dc.relation.volume204-
dc.identifier.doi10.2214/AJR.14.12871-
dc.relation.page396-401-
dc.relation.journalAMERICAN JOURNAL OF ROENTGENOLOGY-
dc.contributor.googleauthorChoi, Woo Jung-
dc.contributor.googleauthorPark, Jeong Seon-
dc.contributor.googleauthorKoo, Hye Ryoung-
dc.contributor.googleauthorKim, Soo-Yeon-
dc.contributor.googleauthorChung, Min Sung-
dc.contributor.googleauthorTae, Kyung-
dc.relation.code2015002061-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidhuilings-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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