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dc.contributor.author이오영-
dc.date.accessioned2016-08-04T02:29:11Z-
dc.date.available2016-08-04T02:29:11Z-
dc.date.issued2015-02-
dc.identifier.citationJournal of Gastrointestinal Surgery, v. 19, NO 2, Page. 242-250en_US
dc.identifier.issn1091-255X-
dc.identifier.issn1873-4626-
dc.identifier.urihttp://link.springer.com/article/10.1007/s11605-014-2682-2-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/22408-
dc.description.abstractThe relationship between fat distribution and lymph node metastasis has not been well studied. The goal of this study was to determine the impact of visceral obesity on lymph node metastasis in gastric cancer. Metastatic lymph node ratio (MLR) was defined as the number of involved nodes by tumor divided by the total number of resected lymph nodes. Visceral (VFA) and subcutaneous fat areas (SFA) were determined by measuring abdominal fat volume distribution via CT scan, and visceral obesity was defined as a VFA to total fat area ratio (V/T) > 0.29. With lymph node metastasis as a dependent variable, the following factors were significant in multivariate analysis among 495 patients: pathologic T stage (P < 0.001), lympho-vascular invasion (P < 0.001), and V/T (hazard ratio (HR) = 0.455, 95 % confidence interval (CI) = 0.263-0.786, P = 0.005). Similarly, when MLR was the dependent variable in multivariate analysis, MLR was significantly associated with lympho-vascular invasion (HR = 2.222, 95 % CI = 1.149-4.296, P = 0.018), and V/T (HR = 0.247, 95 % CI = 0.133-0.458, P < 0.001). Visceral obesity defined by higher visceral to total fat area ratio was significantly associated with decreased MLR.en_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.subjectObesityen_US
dc.subjectVisceral fat areaen_US
dc.subjectLymph nodeen_US
dc.subjectMetastasisen_US
dc.subjectGastric canceren_US
dc.titleInverse association between visceral obesity and lymph node metastasis in gastric cancer.en_US
dc.typeArticleen_US
dc.relation.no2-
dc.relation.volume19-
dc.identifier.doi10.1007/s11605-014-2682-2-
dc.relation.page242-250-
dc.relation.journalJournal of Gastrointestinal Surgery-
dc.contributor.googleauthorPark, Se Woo-
dc.contributor.googleauthorLee, Hang Lak-
dc.contributor.googleauthorJu, Yong Won-
dc.contributor.googleauthorJun, Dae Won-
dc.contributor.googleauthorLee, Oh Young-
dc.contributor.googleauthorHan, Dong Soo-
dc.contributor.googleauthorYoon, Byung Chul-
dc.contributor.googleauthorChoi, Ho Soon-
dc.contributor.googleauthorHahm, Joon Soo-
dc.relation.code2015029337-
dc.sector.campusS-
dc.sector.daehakCOLLEGE OF MEDICINE[S]-
dc.sector.departmentDEPARTMENT OF MEDICINE-
dc.identifier.pidleeoy-
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COLLEGE OF MEDICINE[S](의과대학) > MEDICINE(의학과) > Articles
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