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dc.contributor.author최종훈-
dc.date.accessioned2016-06-17T05:00:18Z-
dc.date.available2016-06-17T05:00:18Z-
dc.date.issued2015-01-
dc.identifier.citationBULLETIN OF THE KOREAN CHEMICAL SOCIETY, v. 36, NO 3, Page. 822-826en_US
dc.identifier.issn1229-5949-
dc.identifier.urihttp://onlinelibrary.wiley.com/doi/10.1002/bkcs.10154/abstract-
dc.identifier.urihttp://hdl.handle.net/20.500.11754/21725-
dc.description.abstractAnthrax is a highly acute disease caused by the bacterium Bacillus anthracis. In this article, we report a highly sensitive detection techniqu e for pathogenic B. anthracis, based on the use of a surface-enhanced Raman scat- tering (SERS)-active magnetic sensor. Gold nanoparticles (GNPs) and magnetic beads were used as SERS nanotags and supporting substrates, respectively. Here, an SERS-based competitive immunoassay platform is described for the quantitative evaluation of the anthrax marker. Poly-γ- D-glutamic acid (PGA) capsules were used as a target biomarker for the highly sensitive detection of B. anthracis because PGA is known to be closely associated with the pathogenesis of B. anthracis infection. The SERS-based competitive assay reveals an extraordinarily high sensitivity for PGA with a limit of detection of ~1.0 ng/mL. This work provides a con- ceptually new immunoassay prototype for fast and sensitive detection of PGA markers.en_US
dc.publisherKOREAN CHEMICAL SOCen_US
dc.subjectSurface-enhanced Raman scatteringen_US
dc.subjectBacillus anthracisen_US
dc.subjectPoly-γ-D-glutamic aciden_US
dc.subjectCompetitive immunoassayen_US
dc.subjectMagnetic beaden_US
dc.titleSurface-Enhanced Raman Scattering-Based Competitive Immunoassay of Poly-γ-D-Glutamic Acid for Highly Sensitive Detection of Anthraxen_US
dc.typeArticleen_US
dc.relation.no3-
dc.relation.volume36-
dc.identifier.doi10.1002/bkcs.10154-
dc.relation.page822-826-
dc.relation.journalBULLETIN OF THE KOREAN CHEMICAL SOCIETY-
dc.contributor.googleauthorKo, Juhui-
dc.contributor.googleauthorCha, Kiweon-
dc.contributor.googleauthorJeon, Jun Ho-
dc.contributor.googleauthorRhie, Gi‐eun-
dc.contributor.googleauthorChoi, Jonghoon-
dc.contributor.googleauthorChoi, Jonghoon-
dc.relation.code2015003699-
dc.sector.campusS-
dc.sector.daehakGRADUATE SCHOOL[S]-
dc.sector.departmentDEPARTMENT OF BIONANOTECHNOLOGY-
dc.identifier.pidjonghchoi-
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GRADUATE SCHOOL[S](대학원) > BIONANOTECHNOLOGY(바이오나노학과) > Articles
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