SYNTHESIS OF N-HETEROPOLYCYCLIC COMPOUNDS INCLUDING QUINAZOLINONE SKELETON USING FRIEDEL-CRAFTS ALKYLATION
- Title
- SYNTHESIS OF N-HETEROPOLYCYCLIC COMPOUNDS INCLUDING QUINAZOLINONE SKELETON USING FRIEDEL-CRAFTS ALKYLATION
- Author
- 오창호
- Keywords
- Friedel–Crafts alkylation; Knoevenagel condensation; N-heteropolycycle; quinazolinone
- Issue Date
- 2015-01
- Publisher
- TAYLOR & FRANCIS INC
- Citation
- SYNTHETIC COMMUNICATIONS, v. 45, NO 6, Page. 758-776
- Abstract
- A simple method to synthesize N-heteropolycyclic quinazolinones was developed including Knoevenagel condensation of quinazolines and aldehydes and Friedel-Craft alkylation as key steps. Knoevenagel reaction of 2-methyl-3-phenylquinazolin-4(3H)-one proceeded smoothly under a basic condition and subsequent Friedel-Craft alkylation with BrOnsted acid gave the N-heteropolycyclic quinazolinones in good yields. Furthermore, these new polycyclic compounds were converted into organic molecules having a long -conjugation system by treatment of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) to utilize them as organic dyes.
- URI
- http://hdl.handle.net/20.500.11754/21641http://www.tandfonline.com/doi/full/10.1080/00397911.2014.987353?scroll=top&needAccess=true
- ISSN
- 0039-7911
- DOI
- 10.1080/00397911.2014.987353
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > CHEMISTRY(화학과) > Articles
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