Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이승환 | - |
dc.date.accessioned | 2024-07-05T02:07:22Z | - |
dc.date.available | 2024-07-05T02:07:22Z | - |
dc.date.issued | 2022-11-09 | - |
dc.identifier.citation | ACS SENSORS, v. 7, no 11, page. 3399-3408 | en_US |
dc.identifier.issn | 2379-3694 | en_US |
dc.identifier.uri | https://pubs.acs.org/doi/full/10.1021/acssensors.2c01507 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/191160 | - |
dc.description.abstract | Recently, various bioelectronic nose devices based on human receptors were developed for mimicking a human olfactory system. However, such bioelectronic nose devices could operate in an aqueous solution, and it was often very difficult to detect insoluble gas odorants. Here, we report a portable bioelectronic nose platform utilizing a receptor protein-based bioelectronic nose device as a sensor and odorant-binding protein (OBP) as a transporter for insoluble gas molecules in a solution, mimicking the functionality of human mucosa. Our bioelectronic nose platform based on I7 receptor exhibited dose-dependent responses to octanal gas in real time. Furthermore, the bioelectronic platforms with OBP exhibited the sensor sensitivity improved by similar to 100% compared with those without OBP. We also demonstrated the detection of odorant gas from real orange juice and found that the electrical responses of the devices with OBP were much larger than those without OBP. Since our bioelectronic nose platform allows us to directly detect gas-phase odorant molecules including a rather insoluble species, it could be a powerful tool for versatile applications and basic research based on a bioelectronic nose. | en_US |
dc.description.sponsorship | This work was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (MSIT) o f Korea (Nos. 2013M3A6B2078961, 2020R1A2B5B02002152, 2018R1A2B3004498, and 2021R1F1A1062909) and the Ministry of Education (No. 2018R1A6A1A03024231). S.h.L. would like to acknowledge the support from the Technology Innovation Program funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea) (No. 20008414). S.H. would like to acknowledge the support from the Ministry of Trade, Industry & Energy (MOTIE, Korea) (No. 20012390), Samsung Electronics Co., Ltd. (No. 201209-07908-01), and the European Research Council (ERC) under the European Union’s Horizon 2020 program (grant agreement no. 682286). | en_US |
dc.language | en_US | en_US |
dc.publisher | AMER CHEMICAL SOC | en_US |
dc.relation.ispartofseries | v. 7, no 11;3399-3408 | - |
dc.subject | odorant-binding protein | en_US |
dc.subject | direct gas sensing, nanodisc | en_US |
dc.subject | carbon nanotube field-effect transistor | en_US |
dc.subject | biosensor platform | en_US |
dc.title | Bioelectrical Nose Platform Using Odorant-Binding Protein as a Molecular Transporter Mimicking Human Mucosa for Direct Gas Sensing | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1021/acssensors.2c01507 | en_US |
dc.relation.page | 3399-3408 | - |
dc.relation.journal | ACS SENSORS | - |
dc.contributor.googleauthor | Choi, Danmin | - |
dc.contributor.googleauthor | Lee, Se June | - |
dc.contributor.googleauthor | Baek, Dahee | - |
dc.contributor.googleauthor | Kim, So-ong | - |
dc.contributor.googleauthor | Shin, Junghyun | - |
dc.contributor.googleauthor | Choi, Yoonji | - |
dc.contributor.googleauthor | Cho, Youngtak | - |
dc.contributor.googleauthor | Bang, Sunwoo | - |
dc.contributor.googleauthor | Park, Jae Yeol | - |
dc.contributor.googleauthor | Lee, Seung Hwan | - |
dc.relation.code | 2022041595 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF BIONANO ENGINEERING | - |
dc.identifier.pid | vincero78 | - |
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