Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이영복 | - |
dc.date.accessioned | 2024-04-18T01:45:57Z | - |
dc.date.available | 2024-04-18T01:45:57Z | - |
dc.date.issued | 2022-12-23 | - |
dc.identifier.citation | CARBOHYDRATE POLYMERS, v. 304, Page. 1-14 | en_US |
dc.identifier.issn | 0144-8617 | en_US |
dc.identifier.issn | 1879-1344 | en_US |
dc.identifier.uri | https://information.hanyang.ac.kr/#/eds/detail?an=000934904000001&dbId=edswsc | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/189855 | - |
dc.description.abstract | With an increase in the severity of environmental pollution caused by microbeads, the development of biodegradable microcapsules that can be applied in diverse fields has attracted significant attention. The degradation processes are directly related to biodegradable microcapsule creation with high stability and persistence. In this study, biodegradable microcapsules are synthesized via a complex coacervation approach using gelatin and alginate as the capsule main wall materials; additionally, enzyme-induced decomposition mechanisms are proposed by observing spectral changes in proton nuclear magnetic resonance (H-1 NMR) analyses. Additional analytical techniques confirm the chemical structure, morphology, and size distribution of the synthesized capsules; these uniform spherical microcapsules are 20-30 mu m in size and possess a smooth surface. In addition to characterization, the microcapsules were exposed to targeted enzymes to investigate enzymatic effects using short-term and long-term degradation kinetics. Close inspection reveals that determination of the degradation rate constant of the major components in the capsule is feasible, and suggests two types of 4-stage degradation mechanisms that are enzyme-specific. These investigations demonstrate that capsule degradation can be explored in detail using 1H NMR spectroscopy to provide a viable strategy for monitoring degradation properties in the development of new biodegradable polymers. | en_US |
dc.description.sponsorship | This research was supported by the National Research Foundation of Korea (NRF-2022R1A2C4001273), 2022 Research Development Program funded by Ansan Green Environment Center (18-09-03-10-16), and Incheon National University Research Grant in 2018. | en_US |
dc.language | en_US | en_US |
dc.publisher | ELSEVIER SCI LTD | en_US |
dc.relation.ispartofseries | v. 304;1-14 | - |
dc.subject | Biodegradable microcapsules | en_US |
dc.subject | Gelatin | en_US |
dc.subject | Alginate | en_US |
dc.subject | Nuclear magnetic resonance | en_US |
dc.subject | Enzyme kinetics | en_US |
dc.subject | Mechanistic study | en_US |
dc.title | Accurate detection of enzymatic degradation processes of gelatin-alginate microcapsule by H-1 NMR spectroscopy: Probing biodegradation mechanism and kinetics | en_US |
dc.type | Article | en_US |
dc.relation.volume | 304 | - |
dc.identifier.doi | 10.1016/j.carbpol.2022.120490 | en_US |
dc.relation.page | 1-14 | - |
dc.relation.journal | CARBOHYDRATE POLYMERS | - |
dc.contributor.googleauthor | Do, Uyen Thi | - |
dc.contributor.googleauthor | Kim, Jiwon | - |
dc.contributor.googleauthor | Luu, Quy Son | - |
dc.contributor.googleauthor | Nguyen, Quynh Thi | - |
dc.contributor.googleauthor | Jang, Taeho | - |
dc.contributor.googleauthor | Park, Yeeun | - |
dc.contributor.googleauthor | Shin, Hwicheol | - |
dc.contributor.googleauthor | Whiting, Nicholas | - |
dc.contributor.googleauthor | Kang, Dong-Ku | - |
dc.contributor.googleauthor | Lee, Youngbok | - |
dc.relation.code | 2023037520 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY[E] | - |
dc.sector.department | DEPARTMENT OF CHEMICAL AND MOLECULAR ENGINEERING | - |
dc.identifier.pid | yblee | - |
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