Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 성기훈 | - |
dc.date.accessioned | 2024-04-04T06:44:04Z | - |
dc.date.available | 2024-04-04T06:44:04Z | - |
dc.date.issued | 2022-09-06 | - |
dc.identifier.citation | MATERIALS LETTERS | en_US |
dc.identifier.issn | 0167-577X | en_US |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0167577X2201641X | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/189629 | - |
dc.description.abstract | In this study, mesoporous platinum nanozymes (MPNs) were fabricated by a surfactant-based self-assembly method and then used to develop a novel competitive immunoassay for sensitive detection of 25-hydroxyvitamin D3 (25(OH)VD3). The MPNs showed enhanced peroxidase-like activity that catalyzes the reaction between hydrogen peroxide (H2O2) and 3,3 ',5,5 '-tetramethylbenzidine (TMB). The excellent peroxidase-like MPNs were employed to develop a competitive immunoassay for the sensitive colorimetric detection of 25(OH)VD3. The immunoassay detected 25(OH)VD3 in the range of 1.6 to 100 ng/mL, with a detection limit of 1.0 ng/mL. The recovery values of 25(OH)VD3 from the spiked human serum samples were between 104% and 95%. These results indicate the applicability of MPNs as alternatives for natural enzymes and the feasibility for sensitive 25 (OH)VD3 detection. | en_US |
dc.description.sponsorship | This research was supported by Basic Science Research Program through the National Research Foundation (NRF) of Korea (2018R1A6A1A03024231 and 2021R1A2C1003566). | en_US |
dc.language | en_US | en_US |
dc.publisher | ELSEVIER | en_US |
dc.relation.ispartofseries | v. 330;133286-133289 | - |
dc.subject | Vitamin D | en_US |
dc.subject | Nanozymes | en_US |
dc.subject | Mesoporous nanoparticles | en_US |
dc.subject | Competitive immunoassay | en_US |
dc.subject | Colorimetry | en_US |
dc.title | Mesoporous platinum nanozyme-based competitive immunoassay for sensitive detection of 25-hydroxyvitamin D | en_US |
dc.type | Article | en_US |
dc.relation.volume | 330 | - |
dc.identifier.doi | https://doi.org/10.1016/j.matlet.2022.133286 | en_US |
dc.relation.page | 133286-133289 | - |
dc.relation.journal | MATERIALS LETTERS | - |
dc.contributor.googleauthor | Lee, Han Been | - |
dc.contributor.googleauthor | Son, Seong Eun | - |
dc.contributor.googleauthor | Gupta, Pramod K. | - |
dc.contributor.googleauthor | Venkatesan, Jayachandran | - |
dc.contributor.googleauthor | Hur, Won | - |
dc.contributor.googleauthor | Park, Jiyeon | - |
dc.contributor.googleauthor | Kim, Seong Nyeon | - |
dc.contributor.googleauthor | Seong, Gi Hun | - |
dc.relation.code | 2023039868 | - |
dc.sector.campus | E | - |
dc.sector.daehak | COLLEGE OF ENGINEERING SCIENCES[E] | - |
dc.sector.department | DEPARTMENT OF BIONANO ENGINEERING | - |
dc.identifier.pid | ghseong | - |
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