Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 원호식 | - |
dc.date.accessioned | 2023-07-21T04:35:16Z | - |
dc.date.available | 2023-07-21T04:35:16Z | - |
dc.date.issued | 2018-06 | - |
dc.identifier.citation | Natural product communications, v. 13, NO. 6, Page. 683-685 | - |
dc.identifier.issn | 1934-578X;1555-9475 | - |
dc.identifier.uri | https://journals.sagepub.com/doi/10.1177/1934578X1801300608 | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/184128 | - |
dc.description.abstract | A new beta-carboline alkaloid, 3,4-dihydrohyrtiosulawesine (8), and fifteen known alkaloids were isolated from the tropical marine sponge Hyrtios sp. Among these known compounds, beta-ketoserotonin (10) has been isolated for the first time from a natural source. The structures of the isolated compounds were determined by spectroscopic analyses and comparison with literature values. Compound 8 displayed potent inhibitory activities against isocitrate lyase (IC50: 92.9 mu M) from Candida albicans. | - |
dc.description.sponsorship | We are grateful to the Department of Marine Resources, State of Chuuk, Federated States of Micronesia, for allowing marine organisms research. This study was supported bygrants from the Korea Institute of Ocean Science and Technology(PE99612) and the Ministry of Oceans and Fisheries (PM60521), Korea. | - |
dc.language | en | - |
dc.publisher | Natural Product Communications | - |
dc.subject | Hyrtios sp. | - |
dc.subject | beta-Carboline alkaloids | - |
dc.subject | Isocitrate lyase | - |
dc.title | Indole Alkaloids from Tropical Sponge Hyrtios sp as Isocitrate Lyase Inhibitors | - |
dc.type | Article | - |
dc.relation.no | 6 | - |
dc.relation.volume | 13 | - |
dc.identifier.doi | 10.1177/1934578x1801300608 | - |
dc.relation.page | 683-685 | - |
dc.relation.journal | Natural product communications | - |
dc.contributor.googleauthor | Park, Seung-Il | - |
dc.contributor.googleauthor | Lee, Yeon-Ju | - |
dc.contributor.googleauthor | Won, Hoshik | - |
dc.contributor.googleauthor | Oh, Ki-Bong | - |
dc.contributor.googleauthor | Lee, Hyi-Seung | - |
dc.sector.campus | E | - |
dc.sector.daehak | 과학기술융합대학 | - |
dc.sector.department | 화학분자공학과 | - |
dc.identifier.pid | hswon | - |
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