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dc.contributor.author성기훈-
dc.date.accessioned2023-07-14T01:16:52Z-
dc.date.available2023-07-14T01:16:52Z-
dc.date.issued2007-04-
dc.identifier.citationANALYTICAL SCIENCES, v. 23, NO. 4, Page. 401-405-
dc.identifier.issn0910-6340;1348-2246-
dc.identifier.urihttps://link.springer.com/article/10.2116/analsci.23.401en_US
dc.identifier.urihttps://repository.hanyang.ac.kr/handle/20.500.11754/183587-
dc.description.abstractA rapid DNA analysis has been developed based on a fluorescence intensity change of a molecular beacon in a PDMS microfluidic channel. Recently, we reported a new analytical method of DNA hybridization involving a PDMS microfluidic sensor using fluorescence energy transfer (FRET). However, there are some limitations in its application to real DNA samples because the target DNA must be labelled with a suitable fluorescent dye. To resolve this problem, we have developed a new DNA microfluidic sensor using a molecular beacon. By monitoring the change in the restored fluorescence intensity along the channel length, it is possible to rapidly detect any hybridization of the molecular beacon to the target DNA. In this case, the target DNA does not need to be labelled. Our experimental results demonstrate that this microfluidic sensor using a molecular beacon is a promising diagnostic tool for rapid DNA hybridization analysis.-
dc.languageen-
dc.publisherJAPAN SOC ANALYTICAL CHEMISTRY-
dc.titleRapid DNA hybridization analysis using a PDMS microfluidic sensor and a molecular beacon-
dc.typeArticle-
dc.relation.no4-
dc.relation.volume23-
dc.identifier.doi10.2116/analsci.23.401-
dc.relation.page401-405-
dc.relation.journalANALYTICAL SCIENCES-
dc.contributor.googleauthorKim, Sungyong-
dc.contributor.googleauthorChen, Lingxin-
dc.contributor.googleauthorLee, Sangyeop-
dc.contributor.googleauthorSeong, Gi Hun-
dc.contributor.googleauthorChoo, Jaebum-
dc.contributor.googleauthorLee, Eun Kyu-
dc.contributor.googleauthorOh, Chil-Hwan-
dc.contributor.googleauthorLee, Sanghoon-
dc.sector.campusE-
dc.sector.daehak공학대학-
dc.sector.department생명나노공학과-
dc.identifier.pidghseong-
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COLLEGE OF ENGINEERING SCIENCES[E](공학대학) > BIONANO ENGINEERING(생명나노공학과) > Articles
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