Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 성기훈 | - |
dc.date.accessioned | 2023-07-12T01:05:20Z | - |
dc.date.available | 2023-07-12T01:05:20Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.citation | MATERIALS LETTERS, v. 330, article no. 133286, | - |
dc.identifier.issn | 0167-577X;1873-4979 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0167577X2201641X?via%3Dihub | en_US |
dc.identifier.uri | https://repository.hanyang.ac.kr/handle/20.500.11754/182845 | - |
dc.description.abstract | In this study, mesoporous platinum nanozymes (MPNs) were fabricated by a surfactant-based self-assembly method and then used to develop a novel competitive immunoassay for sensitive detection of 25-hydroxyvitamin D3 (25(OH)VD3). The MPNs showed enhanced peroxidase-like activity that catalyzes the reaction between hydrogen peroxide (H2O2) and 3,3 ',5,5 '-tetramethylbenzidine (TMB). The excellent peroxidase-like MPNs were employed to develop a competitive immunoassay for the sensitive colorimetric detection of 25(OH)VD3. The immunoassay detected 25(OH)VD3 in the range of 1.6 to 100 ng/mL, with a detection limit of 1.0 ng/mL. The recovery values of 25(OH)VD3 from the spiked human serum samples were between 104% and 95%. These results indicate the applicability of MPNs as alternatives for natural enzymes and the feasibility for sensitive 25 (OH)VD3 detection. | - |
dc.description.sponsorship | Acknowledgements This research was supported by Basic Science Research Program through the National Research Foundation (NRF) of Korea (2018R1A6A1A03024231 and 2021R1A2C1003566) . | - |
dc.language | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | Vitamin D | - |
dc.subject | Nanozymes | - |
dc.subject | Mesoporous nanoparticles | - |
dc.subject | Competitive immunoassay | - |
dc.subject | Colorimetry | - |
dc.title | Mesoporous platinum nanozyme-based competitive immunoassay for sensitive detection of 25-hydroxyvitamin D | - |
dc.type | Article | - |
dc.relation.volume | 330 | - |
dc.identifier.doi | 10.1016/j.matlet.2022.133286 | - |
dc.relation.journal | MATERIALS LETTERS | - |
dc.contributor.googleauthor | Lee, Han Been | - |
dc.contributor.googleauthor | Son, Seong Eun | - |
dc.contributor.googleauthor | Gupta, Pramod K. | - |
dc.contributor.googleauthor | Venkatesan, Jayachandran | - |
dc.contributor.googleauthor | Hur, Won | - |
dc.contributor.googleauthor | Park, Jiyeon | - |
dc.contributor.googleauthor | Kim, Seong Nyeon | - |
dc.contributor.googleauthor | Seong, Gi Hun | - |
dc.sector.campus | E | - |
dc.sector.daehak | 공학대학 | - |
dc.sector.department | 생명나노공학과 | - |
dc.identifier.pid | ghseong | - |
dc.identifier.article | 133286 | - |
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