비타민 D의 자가면역, 알레르기, 감염질환에서의 역할
- Title
- 비타민 D의 자가면역, 알레르기, 감염질환에서의 역할
- Other Titles
- Vitamin D in autoimmune, allergic, and infectious diseases
- Author
- 최제민
- Keywords
- vitamin D; immune system; autoimmune; allergy; infection
- Issue Date
- 2022-09
- Publisher
- 한국식품과학회
- Citation
- 식품과학과 산업, v. 55, NO. 3, Page. 276-283
- Abstract
- Vitamin D is a fat-soluble vitamin helps to retain calcium and phosphorus but also has shown to affect immune regulation and homeostasis. In humans, vitamin D3 and vitamin D2 and their metabolite has intensively studied in both innate and adaptive immune system that they are important to regulate overwhelmed inflammation.
The vitamin D receptor is a nuclear hormone receptor which regulate various downstream target gene expressions as a transcription factor related to metabolism, immune regulation, etc. Vitamin D deficiency is a high-risk factor for inflammatory diseases like autoimmune disease and allergy. In addition, reduced vitamin D seem to correlate with susceptibility to the virus infection such as HIV and COVID-19. In this review, we will summarize up-to-date vitamin D’s role in various immune cells, immune regulatory functions during autoimmune, allergic, and infectious diseases. We will also discuss about vitamin D supplement effects in human trial studies for COVID-19.
- URI
- http://koreascience.or.kr/article/JAKO202227754874324.pagehttps://repository.hanyang.ac.kr/handle/20.500.11754/177924
- ISSN
- 0257-2397
- DOI
- 10.23093/FSI.2022.55.3.276
- Appears in Collections:
- COLLEGE OF NATURAL SCIENCES[S](자연과학대학) > LIFE SCIENCE(생명과학과) > Articles
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